Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, Manitoba, Canada; The Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada; George and Fay Yee Centre for Healthcare Innovation, Winnipeg, Manitoba, Canada; Department of Food and Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba, Canada; The Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden.
Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, Manitoba, Canada; The Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada.
Ann Allergy Asthma Immunol. 2021 Jan;126(1):83-88.e1. doi: 10.1016/j.anai.2020.09.010. Epub 2020 Sep 18.
Food allergy has a known effect on quality of life (QoL), but this has not been extensively studied during the coronavirus disease 2019 pandemic.
To characterize the levels of anxiety of mothers of children aged 0 to 8 years with food allergy compared with families of children without a food allergy and the health-related QoL among children with food allergy during the coronavirus disease 2019 pandemic.
In a mixed-methods study, Canadian mothers of children aged 0 to 8 years with (cases) and without (controls) food allergy provided demographic data and completed age-appropriate anxiety questionnaires between April 14, 2020, and April 28, 2020. The cases also provided food allergy-related data and completed the Food Allergy Quality of Life Questionnaire. In-depth interviews were subsequently conducted with purposefully selected cases.
In a total of 580 participants, 5.5% were cases and 94.5% were controls. For mothers of children aged 0 to 1.5 years, anxiety levels did not differ between cases and controls. For mothers of children aged 1.5 to 8 years, anxiety levels were higher in cases vs controls (P < .05). Among the cases, neither overall nor domain-specific Food Allergy Quality of Life Questionnaire scores differed between age groups (0-3 vs 4-7 years), even after adjustment for confounding variables, including childcare during the pandemic. Qualitatively, the following 3 themes were identified: unexpected challenges of food shopping; less food-related food anxiety during the pandemic; and differences and delays in food allergy testing and therapy.
Mothers of children with food allergy reported high anxiety and poor health-related QoL. Yet, qualitatively, day-to-day food allergy management was better during the pandemic.
食物过敏已知会影响生活质量（QoL），但在 2019 年冠状病毒病大流行期间，这方面尚未得到广泛研究。
与没有食物过敏的儿童家庭相比，描述在 2019 年冠状病毒病大流行期间，0 至 8 岁食物过敏儿童的母亲焦虑水平，并描述食物过敏儿童的健康相关生活质量。
在一项混合方法研究中，加拿大 0 至 8 岁有（病例）和无（对照）食物过敏儿童的母亲在 2020 年 4 月 14 日至 2020 年 4 月 28 日期间提供了人口统计学数据并完成了适合年龄的焦虑问卷。病例还提供了食物过敏相关数据并完成了食物过敏生活质量问卷。随后对有选择的病例进行了深入访谈。
在总共 580 名参与者中，5.5%为病例，94.5%为对照。对于 0 至 1.5 岁儿童的母亲，病例与对照之间的焦虑水平没有差异。对于 1.5 至 8 岁儿童的母亲，病例的焦虑水平高于对照（P <.05）。在病例中，即使在校正了大流行期间的儿童保育等混杂变量后，整体和特定领域的食物过敏生活质量问卷评分在年龄组（0-3 岁与 4-7 岁）之间也没有差异。定性分析确定了以下 3 个主题：食物购物的意外挑战；大流行期间食物相关食物焦虑减少；食物过敏检测和治疗的差异和延迟。
食物过敏儿童的母亲报告了较高的焦虑和较差的健康相关生活质量。然而，从定性上看，大流行期间日常的食物过敏管理更好。
