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儿童和成人中,起源于肺动脉的异常左冠状动脉(ALCAPA)作为重度二尖瓣反流的隐匿病因:病例报告

Anomalous left coronary artery from the pulmonary artery (ALCAPA) as a concealed cause of severe mitral regurgitation in children and adults: Case reports.

作者信息

Nguyen Bac Hoang, Cao Khang Dang, Thao Pham Thi Hieu, Vo Anh Tuan, Le Khoi Minh

机构信息

Department of General Surgery, University Medical Center, University of Medicine and Pharmacy at Ho Chi Minh City, Viet Nam.

Cardiovascular Center, University Medical Center, Ho Chi Minh City, Viet Nam.

出版信息

Int J Surg Case Rep. 2020;75:147-151. doi: 10.1016/j.ijscr.2020.09.022. Epub 2020 Sep 11.

Abstract

INTRODUCTION

Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital coronary artery anomaly and is a concealed cause of mitral regurgitation.

PRESENTATION OF CASE

We reported two cases of severe mitral regurgitation in whom the presence of ALCAPA was overlooked in the first cardiac surgery. In the first case, ALCAPA was diagnosed one year after the mitral annuloplasty and the surgical reimplantation was successfully performed. In the second case, ALCAPA was incidentally detected on multislice computerized tomography during preoperative workup for the second surgery to replace the dehiscent mitral prosthesis.

DISCUSSION

The clinical presentation of ALCAPA varies highly. It is not difficult to diagnose an ALCAPA in newborns and infants. Contrarily, ALCAPA in children and adults can be overlooked.

CONCLUSION

Physicians should always look for the presence of ALCAPA in patients who present with unexplained mitral regurgitation. The surgical strategy in patients with ALCAPA should be carefully individualised to achieve an optimal outcome and alleviate complications.

摘要

引言

左冠状动脉起源于肺动脉(ALCAPA)是一种罕见的先天性冠状动脉异常,是二尖瓣反流的潜在原因。

病例介绍

我们报告了两例严重二尖瓣反流病例,在首次心脏手术中均忽略了ALCAPA的存在。第一例中,二尖瓣环成形术后一年诊断出ALCAPA,并成功进行了手术再植入。第二例中,在第二次手术更换裂开的二尖瓣人工瓣膜的术前检查中,多层计算机断层扫描偶然发现了ALCAPA。

讨论

ALCAPA的临床表现差异很大。诊断新生儿和婴儿的ALCAPA并不困难。相反,儿童和成人的ALCAPA可能被忽视。

结论

对于出现不明原因二尖瓣反流的患者,医生应始终排查ALCAPA的存在。对于ALCAPA患者的手术策略应仔细个体化,以实现最佳结果并减轻并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/450a/7508687/f09ee484ee06/gr1.jpg

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