Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
J Ren Nutr. 2021 May;31(3):313-319. doi: 10.1053/j.jrn.2020.07.006. Epub 2020 Sep 18.
This study aimed to investigate the relationships among obesity, anthropometries, and the dietary inflammatory index (DII) with different aspects of quality of life (QoL) in patients undergoing hemodialysis.
In 83 patients representing a range of body weights, QoL (based on short form 36), DII (extracted from dietary recalls), malnutrition-inflammation score, and anthropometric measurements were assessed.
Obese patients had lower physical health score (mean difference [MD] 9.1, 95% confidence interval [CI] 0.3-17.8, P = .04), physical functioning (MD 10.5, 95% CI 0.7-20.2, P = .04), and bodily pain scores (MD 16.0, 95% CI 3.6-28.4, P = .01) than normal weight group. Patients with abdominal obesity and those with the highest body fat percentage had also lower QoL in many aspects, irrespective of body mass index. The physical (MD 13.2, 95% CI 2.05-24.3, P = .02) and mental (MD 18.4, 95% CI 7.51-29.2, P = .001) health scores, and physical functioning (MD 13.5, 95% CI 1.8-25.2, P = .02), role-physical (MD 25.8, 95% CI 3.0-48.6, P = .03), role-emotional (MD 22.1, 95% CI 5.4-52.8, P = .02), vitality (MD 18.4, 95% CI 7.6-29.3, P = .001), mental health (MD 11.7, 95% CI 3.06-20.4, P = .009), and social functioning (MD 14.2, 95% CI 1.13-27.2, P = .03) were considerably lower in patients with the highest versus the lowest DII. QoL did not differ between normal-weight and obese patients with low DII (P = .26), and between normal-weight and obese patients with high DII (P = .13). Obese patients with low DII also had better QoL than normal-weight subjects with high DII scores.
A diet with higher proinflammatory potential was associated with decreased QoL, irrespective of obesity status. Adherence to a low-DII diet might protect against some obesity-associated complications, a finding that needs further investigations.
本研究旨在探讨肥胖、人体测量学和饮食炎症指数（DII）与接受血液透析患者不同方面的生活质量（QoL）之间的关系。
在 83 名代表不同体重的患者中，评估了 QoL（基于简短表格 36）、DII（从饮食回忆中提取）、营养不良-炎症评分和人体测量学测量。
与正常体重组相比，肥胖患者的身体健康评分（平均差异 [MD] 9.1，95%置信区间 [CI] 0.3-17.8，P=0.04）、身体机能（MD 10.5，95% CI 0.7-20.2，P=0.04）和身体疼痛评分（MD 16.0，95% CI 3.6-28.4，P=0.01）较低。腹部肥胖患者和体脂百分比最高的患者，无论 BMI 如何，在许多方面的 QoL 也较低。身体（MD 13.2，95% CI 2.05-24.3，P=0.02）和精神（MD 18.4，95% CI 7.51-29.2，P=0.001）健康评分，身体机能（MD 13.5，95% CI 1.8-25.2，P=0.02），角色身体（MD 25.8，95% CI 3.0-48.6，P=0.03），角色情感（MD 22.1，95% CI 5.4-52.8，P=0.02），活力（MD 18.4，95% CI 7.6-29.3，P=0.001），心理健康（MD 11.7，95% CI 3.06-20.4，P=0.009）和社会功能（MD 14.2，95% CI 1.13-27.2，P=0.03）在 DII 最高的患者中明显低于 DII 最低的患者。正常体重和 DII 低的肥胖患者之间的 QoL 没有差异（P=0.26），正常体重和 DII 高的肥胖患者之间的 QoL 也没有差异（P=0.13）。DII 低的肥胖患者的 QoL 也优于 DII 高的正常体重患者。
饮食中促炎潜力较高与 QoL 下降有关，无论肥胖状况如何。遵循低 DII 饮食可能有助于预防一些与肥胖相关的并发症，这一发现需要进一步研究。
