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COVID-19大流行期间的一例误导性巨细胞病毒心肌炎:病例报告

A misleading CMV myocarditis during the COVID-19 pandemic: case report.

作者信息

Oualim Sara, Elouarradi Amal, Hafid Sara, Naitelhou Abdelhamid, Sabry Mohamed

机构信息

Department of cardiology, Cheick Khalifa International University Hospital, Mohammed VI University of Health Sciences (UM6SS), Casablanca, Morocco.

Department of internal medecine, Cheick Khalifa International University Hospital, Mohammed VI University of Health Sciences (UM6SS), Casablanca, Morocco.

出版信息

Pan Afr Med J. 2020 Jul 9;36:167. doi: 10.11604/pamj.2020.36.167.23922. eCollection 2020.

Abstract

Coronavirus disease 2019 (COVID-19) has been reported as the possible cause of acute myocarditis. Myocarditis is an inflammatory heart disease mostly caused by viral infections. Cytomegalovirus (CMV) primary infection is often not suspected as a cause of myocarditis in immune-competent adults. We report the case of a 37-year-old male admitted with fever, cough and dyspnea. Chest CT showed typical ground-glass changes indicative of viral pneumonia. He was tested negative for COVID-19 but had biological markers that made us still suspect it. He had elevated troponin I level (up to 111.5 ng/mL) and diffuse myocardial dyskinesia along with a decreased left ventricular ejection fraction (LVEF). He was diagnosed with CMV myocarditis with cardiac insufficiency and totally recovered without antiviral therapy. During the COVID-19 pandemic patients may develop myocarditis, still every myocarditis is not a COVID infection. Myocarditis linked to CMV infection may be rare, but life-threatening.

摘要

2019冠状病毒病(COVID-19)已被报道为急性心肌炎的可能病因。心肌炎是一种主要由病毒感染引起的炎症性心脏病。巨细胞病毒(CMV)原发性感染在免疫功能正常的成年人中通常不被怀疑是心肌炎的病因。我们报告一例37岁男性患者,因发热、咳嗽和呼吸困难入院。胸部CT显示典型的磨玻璃样改变,提示病毒性肺炎。他的COVID-19检测呈阴性,但有一些生物学指标使我们仍怀疑患有该病。他的肌钙蛋白I水平升高(高达111.5 ng/mL),伴有弥漫性心肌运动障碍及左心室射血分数(LVEF)降低。他被诊断为CMV心肌炎伴心功能不全,未经抗病毒治疗完全康复。在COVID-19大流行期间,患者可能会发生心肌炎,但并非所有心肌炎都是COVID感染所致。与CMV感染相关的心肌炎可能很少见,但危及生命。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f105/7467893/8395571a116d/PAMJ-36-167-g001.jpg

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