Sarumathi D, Anitha G, R Deepashree, Thilak C Rajeev, Sastry Apurba S
Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, IND.
Cardiothoracic Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, IND.
Cureus. 2020 Aug 18;12(8):e9827. doi: 10.7759/cureus.9827.
Infective endocarditis (IE) is an infrequent endovascular disease, which can result in significant mortality and morbidity. and viridans streptococci remain the most common etiological agent. , a member of the HACEK ( species, species, , , and species) group of fastidious gram-negative bacillus, is a part of normal upper respiratory flora and a rare cause implicated in IE. Cases of endocarditis are being increasingly reported in last few years due to advancement in automated blood culture system such as BacT/ALERT Virtuo and identification system such as MALDI-TOF MS (matrix-assisted laser desorption/ionization time-of-flight mass spectrometry). We herein report a first case of endocarditis in a pregnant woman at 20 weeks of gestation. Following spontaneous abortion and evacuation of the fetus, appropriate surgical intervention under heparinized condition and pathogen-directed medical intervention was initiated in this patient. This case report highlights the importance of appropriate antimicrobial therapy, which augments earlier resolution of the disease.
感染性心内膜炎（IE）是一种罕见的血管内疾病，可导致显著的死亡率和发病率。草绿色链球菌仍然是最常见的病原体。嗜沫嗜血杆菌是苛养革兰氏阴性杆菌HACEK（嗜血杆菌属、放线杆菌属、人心杆菌属、埃肯菌属和金氏杆菌属）组的成员，是正常上呼吸道菌群的一部分，也是IE的罕见病因。由于自动血培养系统（如BacT/ALERT Virtuo）和鉴定系统（如基质辅助激光解吸/电离飞行时间质谱仪MALDI-TOF MS）的进步，近年来嗜沫嗜血杆菌心内膜炎的病例报告越来越多。我们在此报告一例妊娠20周孕妇的嗜沫嗜血杆菌心内膜炎首例病例。在自然流产和胎儿排出后，对该患者在肝素化条件下进行了适当的手术干预，并进行了针对病原体的药物干预。本病例报告强调了适当抗菌治疗的重要性，这有助于疾病的早期缓解。
