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经皮二尖瓣修复:当前及未来的器械

Percutaneous mitral repair: current and future devices.

作者信息

Estévez-Loureiro Rodrigo, Benito-González Tomás, Garrote-Coloma Carmen, Fernández-Vázquez Felipe, Avanzas Pablo, Piñón Miguel, Pascual Isaac

机构信息

Interventional Cardiology Unit, Hospital Álvaro Cunqueiro, Vigo, Spain.

Interventional Cardiology Unit, Complejo Asistencial Universitario de Leon, Spain.

出版信息

Ann Transl Med. 2020 Aug;8(15):963. doi: 10.21037/atm.2020.03.154.

DOI:10.21037/atm.2020.03.154
PMID:32953763
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7475444/
Abstract

Mitral regurgitation (MR) is the second most common valvular heart disease and its prevalence is increasing with population ageing. In the recent years we have witnessed the development of several transcatheter devices to correct MR in patients at high-risk for surgery. The majority of evidence regarding safety and efficacy of this new therapy comes from MitraClip studies. However, new alternatives on the field of valve repair have emerged with promising results. The aim of this review is to portrait the landscape of transcatheter mitral repair alternatives, from currently used devices to those that will have a role in the near future.

摘要

二尖瓣反流(MR)是第二常见的心脏瓣膜疾病,其患病率随着人口老龄化而增加。近年来,我们见证了几种经导管装置的发展,用于纠正手术高危患者的二尖瓣反流。关于这种新疗法安全性和有效性的大多数证据来自MitraClip研究。然而,瓣膜修复领域出现了新的替代方案,并取得了令人鼓舞的结果。本综述的目的是描绘经导管二尖瓣修复替代方案的全景,从目前使用的装置到在不久的将来将发挥作用的装置。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d405/7475444/2f8abc809a6e/atm-08-15-963-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d405/7475444/8e4ad2bc131a/atm-08-15-963-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d405/7475444/3492d017a2ea/atm-08-15-963-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d405/7475444/1af379d0250e/atm-08-15-963-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d405/7475444/2f8abc809a6e/atm-08-15-963-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d405/7475444/8e4ad2bc131a/atm-08-15-963-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d405/7475444/3492d017a2ea/atm-08-15-963-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d405/7475444/1af379d0250e/atm-08-15-963-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d405/7475444/2f8abc809a6e/atm-08-15-963-f4.jpg

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Simultaneous transcatheter treatment of ascending aortic aneurysm with aortic and mitral regurgitation: an in vitro study.升主动脉瘤合并主动脉瓣和二尖瓣反流的经导管同期治疗:一项体外研究。
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本文引用的文献

1
Echocardiographic Outcomes After Transcatheter Leaflet Approximation in Patients With Secondary Mitral Regurgitation: The COAPT Trial.经导管瓣叶接近术治疗继发性二尖瓣反流患者的超声心动图结果:COAPT 试验。
J Am Coll Cardiol. 2019 Dec 17;74(24):2969-2979. doi: 10.1016/j.jacc.2019.09.017. Epub 2019 Sep 28.
2
The REDUCE FMR Trial: A Randomized Sham-Controlled Study of Percutaneous Mitral Annuloplasty in Functional Mitral Regurgitation.REDUCE FMR 试验:经皮二尖瓣成形术治疗功能性二尖瓣反流的随机假手术对照研究。
JACC Heart Fail. 2019 Nov;7(11):945-955. doi: 10.1016/j.jchf.2019.06.011. Epub 2019 Sep 11.
3
Effect of Successful Edge-to-Edge Mitral Valve Repair on Ventricular Arrhythmic Burden in Patients With Functional Mitral Regurgitation and Implantable Cardiac Devices.
功能性二尖瓣反流合并植入式心脏装置患者成功二尖瓣瓣缘对缘修复术对室性心律失常负担的影响。
Am J Cardiol. 2019 Oct 1;124(7):1113-1119. doi: 10.1016/j.amjcard.2019.06.027. Epub 2019 Jul 16.
4
Transcatheter Valve Repair for Patients With Mitral Regurgitation: 30-Day Results of the CLASP Study.经导管二尖瓣修复术治疗二尖瓣反流患者:CLASP 研究的 30 天结果。
JACC Cardiovasc Interv. 2019 Jul 22;12(14):1369-1378. doi: 10.1016/j.jcin.2019.04.034. Epub 2019 Jun 26.
5
MitraClip improves cardiopulmonary exercise test in patients with systolic heart failure and functional mitral regurgitation.经导管二尖瓣夹合术改善收缩性心力衰竭伴功能性二尖瓣反流患者的心肺运动试验结果。
ESC Heart Fail. 2019 Aug;6(4):867-873. doi: 10.1002/ehf2.12457. Epub 2019 Jun 11.
6
Transcatheter Mitral Valve Direct Annuloplasty with the Millipede IRIS Ring.使用千足虫IRIS环进行经导管二尖瓣直接瓣环成形术
Interv Cardiol Clin. 2019 Jul;8(3):261-267. doi: 10.1016/j.iccl.2019.02.001. Epub 2019 Apr 8.
7
Health Status After Transcatheter Mitral-Valve Repair in Heart Failure and Secondary Mitral Regurgitation: COAPT Trial.心力衰竭伴继发性二尖瓣反流患者行经导管二尖瓣修复术后的健康状况:COAPT 试验。
J Am Coll Cardiol. 2019 May 7;73(17):2123-2132. doi: 10.1016/j.jacc.2019.02.010. Epub 2019 Mar 17.
8
Transcatheter Mitral-Valve Repair in Patients with Heart Failure.经导管二尖瓣修复术治疗心力衰竭患者。
N Engl J Med. 2018 Dec 13;379(24):2307-2318. doi: 10.1056/NEJMoa1806640. Epub 2018 Sep 23.
9
Percutaneous Repair or Medical Treatment for Secondary Mitral Regurgitation.经皮修复或药物治疗继发性二尖瓣反流。
N Engl J Med. 2018 Dec 13;379(24):2297-2306. doi: 10.1056/NEJMoa1805374. Epub 2018 Aug 27.
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Transcatheter mitral valve repair for functional mitral regurgitation using the Cardioband system: 1 year outcomes.经导管二尖瓣修复术治疗功能性二尖瓣反流:1 年结果。
Eur Heart J. 2019 Feb 1;40(5):466-472. doi: 10.1093/eurheartj/ehy424.