Lazar Andra, Löfkvist Ulrika, Verrecchia Luca, Karltorp Eva
Department of Otolaryngology, Karolinska University Hospital, Stockholm, Sweden.
Department of Clinical Science, Intervention and Technology, Karolinska Institute, Stockholm, Sweden.
Acta Paediatr. 2021 Jan;110(1):30-35. doi: 10.1111/apa.15561. Epub 2020 Nov 5.
This study explored whether there were long-term hearing and vestibular outcome differences between five pairs of identical twins who had been infected with the congenital cytomegalovirus (CMV) infection before birth. Data were collected from the medical records at the Audiological Clinic, Karolinska University Hospital, Stockholm. The congenital CMV infection resulted in high variations in vestibular and hearing function within, and between, the genetically identical twin pairs. Clinicians need to be aware that treatment and interventions may need to differ substantially when identical twins have hearing issues related to the congenital CMV infection.
本研究探讨了五对在出生前感染先天性巨细胞病毒（CMV）的同卵双胞胎之间是否存在长期听力和前庭功能差异。数据收集自斯德哥尔摩卡罗林斯卡大学医院听力诊所的病历。先天性CMV感染导致基因相同的双胞胎对内和对之间的前庭和听力功能存在很大差异。临床医生需要意识到，当同卵双胞胎出现与先天性CMV感染相关的听力问题时，治疗和干预可能需要有很大不同。
