Buchner A, Sciubba J J
Oral Surg Oral Med Oral Pathol. 1987 Jun;63(6):688-97. doi: 10.1016/0030-4220(87)90372-0.
Peripheral (extraosseous or soft tissue) odontogenic tumors are rare lesions that occur in the soft tissue overlying the tooth-bearing areas of the mandible and the maxilla. A review of the English-language literature revealed only 48 well-documented cases of peripheral epithelial odontogenic tumors. Thirty-two were peripheral ameloblastomas; six were peripheral adenomatoid odontogenic tumors; nine were peripheral calcifying epithelial odontogenic tumors; and one was a peripheral squamous odontogenic tumor. An additional four cases were reported as peripheral ameloblastomas in extragingival locations, but their odontogenic origin is debatable. Although the peripheral ameloblastoma is histologically similar to its central counterpart, it differs in its clinical features and biologic behavior. It does not exhibit an aggressive, destructive behavior and does not invade the underlying bone. Conservative excision of the tumor with minimal but adequate margins is the treatment of choice and recurrences are uncommon. This benign biologic behavior appears to be true also for lesions diagnosed as peripheral calcifying epithelial odontogenic tumors and undoubtedly is true for the peripheral adenomatoid odontogenic tumors.
外周性（骨外或软组织）牙源性肿瘤是罕见的病变，发生在下颌骨和上颌骨牙齿萌出区域上方的软组织中。对英文文献的回顾显示，仅有48例记录完备的外周性上皮牙源性肿瘤病例。其中32例为外周性成釉细胞瘤；6例为外周性腺样牙源性肿瘤；9例为外周性钙化上皮牙源性肿瘤；1例为外周性鳞状牙源性肿瘤。另外有4例报告为龈外部位的外周性成釉细胞瘤，但其牙源性起源存在争议。尽管外周性成釉细胞瘤在组织学上与其中心型相似，但其临床特征和生物学行为有所不同。它不表现出侵袭性、破坏性的行为，也不侵犯下方骨质。以最小但足够的切缘对肿瘤进行保守切除是首选的治疗方法，复发并不常见。这种良性生物学行为对于诊断为外周性钙化上皮牙源性肿瘤的病变似乎也是如此，对于外周性腺样牙源性肿瘤无疑也是如此。
