Wang Lihong, Li Pengfei, Kou Jiangcui, Hu Changqing
Department of surgical operating room, Harrison International Peace Hospital, Hebei Province, China.
Medicine (Baltimore). 2020 Sep 18;99(38):e22210. doi: 10.1097/MD.0000000000022210.
Total hip arthroplasty (THA) is a safe and mature surgical method for the treatment of post-traumatic arthritis and end-stage degenerative osteoarthritis. The cohort study regarding the outcomes of THA following acetabulum fracture is sparse. Therefore, we carried out this present retrospective paired cohort study to study the long-term outcomes of patients receiving THA after the acetabular fracture versus patients receiving THA for the primary osteoarthritis.
Patients with posttraumatic arthritis who received the initial THA after open reduction and internal fixation of acetabular fractures or patients with end-stage degenerative osteoarthritis were included in our study. A retrospective review of patients who receiving the primary total hip arthroplasty in the same institution from 2008 to 2015 was conducted. This present retrospective cohort research was authorized via our hospital institutional review committee. The patients in cohort group were matched 2:1 with the patients in study group according to following criteria: body mass index (±3 points), and age at THA time (±3 years), sex, as well as the score of American Society of Anesthesiologists (±1 point). The measure of primary outcome was the improved Harris Hip Score. Secondary outcomes included surgery time, hip range of motion, revision, complications (infection, loosening, polyethylene wear, dislocation, wound complications, deep vein thrombosis, or pulmonary embolism).
It was assumed that there is a remarkable difference in postoperative outcomes between the 2 groups.
This study protocol was registered in Research Registry (researchregistry5921).
全髋关节置换术(THA)是治疗创伤后关节炎和终末期退行性骨关节炎的一种安全且成熟的手术方法。关于髋臼骨折后行THA疗效的队列研究较少。因此,我们开展了这项回顾性配对队列研究,以探讨髋臼骨折后接受THA的患者与原发性骨关节炎接受THA的患者的长期疗效。
本研究纳入髋臼骨折切开复位内固定术后接受初次THA的创伤后关节炎患者或终末期退行性骨关节炎患者。对2008年至2015年在同一机构接受初次全髋关节置换术的患者进行回顾性研究。本回顾性队列研究经我院机构审查委员会批准。队列组患者根据以下标准与研究组患者按2:1进行配对:体重指数(±3分)、THA时年龄(±3岁)、性别以及美国麻醉医师协会评分(±1分)。主要结局指标为Harris髋关节评分改善情况。次要结局指标包括手术时间、髋关节活动范围、翻修、并发症(感染、松动、聚乙烯磨损、脱位、伤口并发症、深静脉血栓形成或肺栓塞)。
假设两组术后疗效存在显著差异。
本研究方案已在Research Registry(researchregistry5921)注册。