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与新型冠状病毒肺炎相关的吉兰-巴雷综合征

Guillain-Barré syndrome associated with COVID-19 disease.

作者信息

Korem Sindhuja, Gandhi Haresh, Dayag Decerie Baculi

机构信息

Internal Medicine, Monmouth Medical Center, Long Branch, New Jersey, USA

Internal Medicine, Monmouth Medical Center, Long Branch, New Jersey, USA.

出版信息

BMJ Case Rep. 2020 Sep 21;13(9):e237215. doi: 10.1136/bcr-2020-237215.

Abstract

Clinical manifestations of COVID-19 are known to be variable with growing evidence of nervous system involvement. In this case report, we describe the symptoms of a patient infected with SARS-CoV-2 whose clinical course was complicated with Guillain-Barré syndrome (GBS). We present a case of a 58-year-old woman who was initially diagnosed with COVID-19 pneumonia due to symptoms of fever and cough. Two weeks later, after the resolution of upper respiratory tract symptoms, she developed symmetric ascending quadriparesis and paresthesias. The diagnosis of GBS was made through cerebrospinal fluid analysis and she was successfully treated with intravenous immunoglobulin administration.

摘要

已知新型冠状病毒肺炎(COVID-19)的临床表现具有多样性,且越来越多的证据表明其会累及神经系统。在本病例报告中,我们描述了一名感染严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的患者的症状,其临床病程并发了吉兰-巴雷综合征(GBS)。我们报告了一例58岁女性患者,她最初因发热和咳嗽症状被诊断为COVID-19肺炎。两周后,上呼吸道症状缓解,她出现了对称性上行性四肢无力和感觉异常。通过脑脊液分析确诊为GBS,她通过静脉注射免疫球蛋白成功治愈。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b73/7507330/be5393f1337c/bcr-2020-237215f01.jpg

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