Department of Traumatology, Military Hospital, Budapest, Hungary.
Department of Morphology and Physiology, Health Sciences Faculty, Semmelweis University, Budapest, Hungary.
Sci Rep. 2020 Sep 21;10(1):15381. doi: 10.1038/s41598-020-71982-z.
In an attempt to induce experimental varicosity, reverse perforant vein development was initiated in the rat leg by applying a chronic (14 and 32 weeks) partial stricture on the main branch of the deep femoral vein. At surfacing of the incompetent perforantes, typical reticular vein plaques and spider veins were identified by video-microscopy and quantitative histology. Deep vein blood was channeled by them into the saphenous vein system, the extra flow deforming these vessels, causing local dilations and broken course, even undulations of larger branches.
为了诱导实验性静脉曲张，通过对股深静脉主干施加慢性（14 和 32 周）部分狭窄来启动大鼠腿部的逆行穿通静脉发育。在功能不全的穿通支显露时，通过视频显微镜和定量组织学鉴定出典型的网状静脉斑块和蜘蛛静脉。深静脉血液通过它们进入大隐静脉系统，额外的血流使这些血管变形，导致局部扩张和中断，甚至较大分支的波动。
