Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, USA.
Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University, Kyoto, Japan.
Breast Cancer. 2021 Nov;28(6):1195-1211. doi: 10.1007/s12282-020-01157-1. Epub 2020 Sep 21.
The purpose of this article is to overview the existing breast cancer screening guidelines for women at high risk from world-leading specialty societies. Accumulation of evidence and development of accessible genetic testing strategies have changed the idea of breast cancer screening for high-risk women. Personalized tailor-made screening adjusted for risk factors has been conducted in accordance with guidelines. The use of imaging modalities other than mammography including contrast-enhanced MRI and other various strategies for improving screening are discussed. The present review also mentions the existing challenges in high-risk screening and the latest information based on two large-scale studies.
本文旨在综述世界领先的专业学会针对高危女性的现有乳腺癌筛查指南。随着证据的积累和可及性遗传检测策略的发展,高危女性的乳腺癌筛查观念发生了改变。根据指南,针对危险因素进行了个体化的定制化筛查。讨论了包括对比增强 MRI 在内的乳腺影像学检查以外的其他影像学方法以及提高筛查效果的其他各种策略。本综述还提到了高危人群筛查中存在的挑战和两项大型研究的最新信息。