意大利的冠状病毒与分娩：一项基于全国人口的队列研究结果。
Coronavirus and birth in Italy: results of a national population-based cohort study.
机构信息
Centro Nazionale di Prevenzione delle Malattie e Promozione della Salute, Istituto Superiore di Sanità, Rome, Italy.
Dipartimento di Biomedicina e Prevenzione, Università degli Studi Tor Vergata, Rome, Italy *the members of the ItOSS COVID-19 Working Group are reported before the References.
出版信息
Ann Ist Super Sanita. 2020 Jul-Sep;56(3):378-389. doi: 10.4415/ANN_20_03_17.
INTRODUCTION
The study was implemented to provide guidance to decision-makers and clinicians by describing hospital care offered to women who gave birth with confirmed SARS-CoV-2 infection.
MATERIALS AND METHODS
National population-based prospective cohort study involving all women with confirmed SARS-CoV-2 infection who gave birth between February 25 and April 22, 2020 in any Italian hospital.
RESULTS
The incidence rate of confirmed SARS-CoV-2 infection in women who gave birth was 2.1 per 1000 maternities at a national level and 6.9/1000 in the Lombardy Region. Overall one third of the women developed a pneumonia and 49.7% assumed at least one drug against SARS-CoV-2 infection. Caesarean rate was 32.9%, no mothers nor newborns died. Six percent of the infants tested positive for SARS-CoV-2 at birth.
CONCLUSIONS
Clinical features and outcomes of COVID-19 in women who gave birth are similar to those described for the general population, most women developing mild to moderate illness.
引言
本研究旨在通过描述确诊感染 SARS-CoV-2 的产妇所接受的医院护理，为决策者和临床医生提供指导。
材料与方法
本研究为全国性基于人群的前瞻性队列研究，纳入了 2020 年 2 月 25 日至 4 月 22 日期间在意大利任何一家医院分娩且确诊感染 SARS-CoV-2 的所有女性。
结果
全国范围内，确诊感染 SARS-CoV-2 的产妇发病率为每千例分娩 2.1 例，伦巴第大区为 6.9/1000。总体而言，三分之一的产妇患有肺炎，49.7%的产妇至少使用了一种针对 SARS-CoV-2 感染的药物。剖宫产率为 32.9%，无产妇和新生儿死亡。出生时，6%的婴儿检测出 SARS-CoV-2 呈阳性。
结论
分娩的 COVID-19 产妇的临床特征和结局与一般人群描述的相似，大多数产妇病情较轻至中度。
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