Royal (Dick) School of Veterinary Studies and Roslin Institute, The University of Edinburgh, Roslin, UK.
School of Veterinary Medicine, University College Dublin, Dublin, Ireland.
J Feline Med Surg. 2021 Apr;23(4):357-363. doi: 10.1177/1098612X20957161. Epub 2020 Sep 22.
The aims of this study were to document the presence and prevalence of feline lipiduria and renal lipid deposition on CT, and to search for associations between the presence of lipiduria and sex, urinary tract abnormalities and urolithiasis.
The CT examinations of 252 cats were reviewed for the presence of an antigravitational hypodense bubble in the urinary bladder with density values between -180 Hounsfield units (HU) and -20 HU. To identify associations between lipiduria and sex, urinary tract abnormalities and urolithiasis, Fisher's exact test was used. Renal cortical density measurement was performed in all cats. The Mann-Whitney test was performed to compare renal cortical density between lipiduric and unaffected cats.
A total of 27 domestic cats (10.7%) had CT evidence of lipiduria. Lipiduric cats had a significantly lower renal cortical density than unaffected cats ( <0.01). Male neutered cats had a significantly higher frequency of lipiduria and lower renal cortical density compared with female neutered cats ( <0.01). There was no significant difference between the groups regarding renal, ureteral or urethral abnormalities.
Lipiduria is a common physiological phenomenon in cats that can be detected on routine CT examinations. Decreased renal cortical density is associated with lipiduria. This may aid in the diagnosis of feline lipiduria and help to differentiate its presence from other pathological depositions and excretions.
本研究旨在记录 CT 上猫的尿脂和肾脂沉积的存在和流行情况，并寻找尿脂存在与性别、尿路异常和尿石症之间的关联。
对 252 只猫的 CT 检查进行了回顾，以寻找在膀胱中存在重力性低衰减气泡的情况，其密度值在-180 亨氏单位（HU）至-20 HU 之间。为了确定尿脂与性别、尿路异常和尿石症之间的关联，使用 Fisher 精确检验。对所有猫进行肾皮质密度测量。使用 Mann-Whitney 检验比较尿脂猫和无尿脂猫的肾皮质密度。
共有 27 只家猫（10.7%）有 CT 证据表明存在尿脂。尿脂猫的肾皮质密度明显低于无尿脂猫（<0.01）。雄性去势猫的尿脂发生率和肾皮质密度明显高于雌性去势猫（<0.01）。各组之间在肾脏、输尿管或尿道异常方面没有显著差异。
尿脂是猫的一种常见生理现象，可在常规 CT 检查中检测到。肾皮质密度降低与尿脂有关。这可能有助于猫尿脂的诊断，并有助于将其与其他病理性沉积和排泄区分开来。
