Division of Otolaryngology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Department of Otorhinolaryngology-Head and Neck Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Otolaryngol Head Neck Surg. 2021 May;164(5):1100-1107. doi: 10.1177/0194599820955172. Epub 2020 Sep 22.
The primary objective was to determine if obstructive sleep apnea (OSA) can improve after adenoidectomy.
Case series with chart review.
Tertiary children's hospital between 2016 and 2018.
The study included children under 3.5 years with small (1+ or 2+) palatine tonsils, large (3+ or 4+) adenoids, and documented OSA on polysomnogram (PSG).
Seventy-one children were included. Age at adenoidectomy was 2.0 years (95% CI, 1.8-2.2) and 71.8% were male. Mean follow-up was 2.5 years (95% CI, 2.3-2.7). Twenty-six children (36.6%) obtained a repeat PSG at a mean of 9.7 months (95% CI, 6.3-13.2) after adenoidectomy. Among those with a postoperative PSG, apnea-hypopnea index decreased in 77.0% (mean, -3.2 events/h; 95% CI, -14.1 to 7.6), and the proportion with moderate to severe OSA decreased from 65.4% to 30.8% ( = .03). Six children (23.1%) had a normal PSG after adenoidectomy. Tonsillectomy was performed in 14.1% of children at 12.1 months (95% CI, 7.5-16.7) after adenoidectomy. Despite similar preoperative PSG variables, younger children (1.5 vs 2.1 years, = .02) were more likely to require tonsillectomy. Substantial adenoid regrowth was identified in 1 child at the time of tonsillectomy.
Adenoidectomy may improve OSA in young children with large adenoids and small tonsils. However, younger age predicted the need for subsequent tonsillectomy. Prospective studies with additional PSG data are necessary to corroborate these findings.
主要目的是确定腺样体切除术是否可以改善阻塞性睡眠呼吸暂停(OSA)。
病例系列,图表回顾。
2016 年至 2018 年期间的三级儿童医院。
研究包括腺样体肥大(3+或 4+)、扁桃体小(1+或 2+)且多导睡眠图(PSG)确诊为 OSA 的 3.5 岁以下儿童。
71 例患儿纳入研究。腺样体切除术年龄为 2.0 岁(95%CI,1.8-2.2),71.8%为男性。平均随访时间为 2.5 年(95%CI,2.3-2.7)。26 例患儿(36.6%)在腺样体切除术后平均 9.7 个月(95%CI,6.3-13.2)行重复 PSG。在接受术后 PSG 的患儿中,呼吸暂停低通气指数降低了 77.0%(平均减少 3.2 次/小时;95%CI,-14.1 至 7.6),中重度 OSA 的比例从 65.4%降至 30.8%( =.03)。6 例患儿(23.1%)腺样体切除术后 PSG 正常。腺样体切除术后 12.1 个月(95%CI,7.5-16.7),14.1%的患儿行扁桃体切除术。尽管术前 PSG 变量相似,但年龄较小的患儿(1.5 岁比 2.1 岁, =.02)更有可能需要行扁桃体切除术。1 例患儿在扁桃体切除时发现腺样体明显再生。
腺样体切除术可改善腺样体肥大、扁桃体小的幼儿 OSA。然而,年龄较小预测需要随后行扁桃体切除术。需要前瞻性研究并结合额外的 PSG 数据来证实这些发现。