Department of Psychiatry, College of Health Sciences, Axum University, Axum, Ethiopia.
Reserach and Training Department, Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia.
Psychiatr Q. 2020 Dec;91(4):1291-1304. doi: 10.1007/s11126-020-09851-1. Epub 2020 Sep 22.
Studies have suggested that suicidal ideation and attempt are highly prevalent among young people with HIV/AIDS and have been linked with increased risk of complete suicide. However, thus far, there are no worldwide systematic reviews and meta-analysis of the prevalence of suicidal ideation and attempt among young people with HIV/AIDS. A systematic search of PubMed, Scopus, and Web was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Prevalence rates from individual studies were pooled by using a random-effect meta-analysis. The quality of included studies was assessed by the Joanna Briggs Institute's quality assessment checklist. We used the Cochran's Q and the I tests to measure heterogeneity across the studies. In total, 14 studies involving 4842 young people with HIV/AIDS were included in this meta-analysis. Our random effect meta-analysis indicated that roughly a quarter of young people with HIV/AIDS had lifetime suicidal ideations [24.38% (95% CI; 18.49-31.44)], and more than one in ten had current [10.33% (95% CI; 6.13-16.88)], and 6 month [13.03% (95% CI; 4.71-31.24)] suicidal ideations. Likewise, a significant proportion of young people with HIV/AIDS had current [3.75% (95% CI; 2.30-6.06)], 6 month [15.33% (95% CI; 10.00-22.78)], and lifetime [13.05% (95% CI; 7.55-21.61)] suicidal attempts. The pooled prevalence estimate of both suicidal ideation and attempts varied according to the sample size of the participants. This study found that a considerable proportion of young people with HIV/AIDS had suicidal ideation and attempt, suggesting the urgent needs of intervention strategies to relieve the suffering and possibly prevent death due to suicide.
研究表明,HIV/AIDS 青少年中自杀意念和自杀未遂的发生率很高,并且与完全自杀的风险增加有关。然而,迄今为止,全球范围内尚无针对 HIV/AIDS 青少年自杀意念和自杀未遂发生率的系统评价和荟萃分析。根据系统评价和荟萃分析的首选报告项目 (PRISMA) 指南,对 PubMed、Scopus 和 Web 进行了系统搜索。通过使用随机效应荟萃分析汇总了来自各个研究的患病率。使用 Joanna Briggs 研究所的质量评估清单评估了纳入研究的质量。我们使用 Cochran's Q 和 I 检验来衡量研究之间的异质性。共有 14 项研究纳入了 4842 名 HIV/AIDS 青少年,本荟萃分析包括这些研究。我们的随机效应荟萃分析表明,大约四分之一的 HIV/AIDS 青少年有过自杀意念[24.38%(95%CI;18.49-31.44)],超过十分之一的人目前有自杀意念[10.33%(95%CI;6.13-16.88)]和 6 个月[13.03%(95%CI;4.71-31.24)]自杀意念。同样,相当一部分 HIV/AIDS 青少年目前有自杀意念[3.75%(95%CI;2.30-6.06)]、6 个月[15.33%(95%CI;10.00-22.78)]和终生[13.05%(95%CI;7.55-21.61)]自杀企图。自杀意念和企图的合并患病率估计值因参与者的样本量而异。这项研究发现,相当一部分 HIV/AIDS 青少年有自杀意念和企图,这表明迫切需要采取干预策略来减轻痛苦,并可能防止自杀导致的死亡。