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腹腔镜动力粉碎术:避免肿瘤播散的技术。

Laparoscopic Power Morcellation: Techniques to Avoid Tumoral Spread.

作者信息

Zapardiel Ignacio, Boria Félix, Halaska Michael J, De Santiago Javier

机构信息

Gynecologic Oncology Unit, La Paz University Hospital (Drs. Zapardiel and Boria), Madrid, Spain.

Gynecologic Oncology Unit, La Paz University Hospital (Drs. Zapardiel and Boria), Madrid, Spain.

出版信息

J Minim Invasive Gynecol. 2021 Aug;28(8):1442-1443. doi: 10.1016/j.jmig.2020.09.012. Epub 2020 Sep 19.

Abstract

STUDY OBJECTIVE

To show 3 different techniques for achieving an endobag morcellation without adding extra time and cost to the surgery.

DESIGN

Stepwise demonstration of the 3 techniques with narrated video footage.

SETTING

Morcellation is a useful procedure for fragmenting and extracting specimens during laparoscopic surgery without the need to perform a laparotomy. Patients who otherwise would not be eligible for minimally invasive surgery (i.e., those with a large uterus or myomas) could benefit from laparoscopic advantages. However, morcellation has a major limitation: the risk of dissemination of unsuspected malignancies. In 2017, the Food and Drug Administration released an updated assessment of the use of laparoscopic power morcellators for treatment of leiomyomas. A total of 23 studies were included in the analysis, and 20 studies (90 910 women) contributed to the estimated prevalence of leiomyosarcoma at the time of surgery for presumed leiomyomas. Depending on the modeling methodology used, the estimated prevalence of uterine sarcoma was 1 in 305 to 1 in 360 women, and for leiomyosarcoma, the estimated prevalence was 1 in 570 to 1 in 750 women [1]. Currently available evidence has suggested that if an undiagnosed uterine malignancy is intra-abdominally morcellated, there is a risk of intraperitoneal dissemination of the disease [2]. Therefore, the European Society of Gynecological Oncology emitted a statement in 2016 recommending avoiding morcellation if there is any suspicion of sarcoma and using endobag containers for morcellation of the surgically removed uterine myomas [3]. In addition, in the United States, the Food and Drug Administration recommends performing laparoscopic power morcellation for myomectomy or hysterectomy only with a tissue containment system, legally marketed in the United States [4].

INTERVENTIONS

There are several techniques described in the literature for contained uterine myomas morcellation [5]. In this video, we present 3 of them: First, an indirect-view morcellation is described. In this technique, we placed the myoma in the bag and exteriorize it through one of the trocars. Once outside the abdomen, we placed the morcellator through the bag opening and did the morcellation inside the bag while checking through the umbilicus camera. Special attention must be paid to avoid any damage to the bag because the visualization is limited in this technique. Second, a direct-view technique is described, in which we exteriorized the opening of a 15-mm bag through the suprapubic trocar and a closed end of the bag through the umbilicus. We made a hole in the umbilicus end of the bag and introduced the camera trocar through it. Once done, we introduced the morcellator through the opening and the camera in the umbilicus port. Third, a single-port-contained morcellation is explained. The bag was exteriorized through the umbilicus, and a skin retractor was placed. A glove was placed outside the retractor to isolate the bag. Once placed, 2 of the fingers were opened and used as trocars (one for the morcellator and the other for a 30° camera). After using this technique, the scope should be replaced to minimize the risk of contamination. The following are possible limitations of each technique: in the indirect-view technique, owing to the limited visualization, the surgeon must pay special attention to avoid tearing the bag while morcellating the specimen. In the direct-view technique method, the surgeon needs to ensure the proper closure of the bag before removing it from the abdomen to avoid possible dissemination risk. Finally, in the single-port technique, the surgeon must have previous experience in this type of approach, minimizing the risk of contamination by changing the scope after the morcellation process.

CONCLUSION

Laparoscopic power morcellation may provide several benefits for our patients, when performing a hysterectomy or a multiple myomectomy. We presented 3 different and feasible techniques for laparoscopic power morcellation using an endobag container.

摘要

研究目的

展示3种不同的技术,能在不增加手术时间和成本的情况下实现内置袋式碎瘤术。

设计

通过带旁白的视频片段对这3种技术进行逐步演示。

背景

碎瘤术是腹腔镜手术中用于破碎和取出标本的一种有用方法,无需进行剖腹手术。否则不符合微创手术条件的患者(即子宫大或有肌瘤的患者)可从腹腔镜手术的优势中获益。然而,碎瘤术有一个主要局限性:未被怀疑的恶性肿瘤播散风险。2017年,美国食品药品监督管理局发布了关于腹腔镜电动碎瘤器用于治疗平滑肌瘤的最新评估。分析共纳入23项研究,20项研究(90910名女性)有助于估计假定为平滑肌瘤的手术时平滑肌肉瘤的患病率。根据所使用的建模方法,子宫肉瘤的估计患病率为每305名女性中有1例至每360名女性中有1例,平滑肌肉瘤的估计患病率为每570名女性中有1例至每750名女性中有1例[1]。目前可得的证据表明,如果未诊断出的子宫恶性肿瘤在腹腔内被碎瘤,存在疾病腹腔播散的风险[2]。因此,欧洲妇科肿瘤学会在2016年发表声明,建议如果怀疑有肉瘤则避免碎瘤,并使用内置袋容器对手术切除的子宫肌瘤进行碎瘤[3]。此外,在美国,食品药品监督管理局建议仅使用在美国合法销售的组织 containment系统进行腹腔镜电动碎瘤术以行肌瘤切除术或子宫切除术[4]。

干预措施

文献中描述了几种用于子宫肌瘤内置碎瘤的技术[5]。在本视频中,我们展示其中3种:第一,描述一种间接视野碎瘤术。在该技术中,我们将肌瘤放入袋中并通过一个套管针将其引出体外。一旦在腹部外,我们通过袋口放入碎瘤器并在袋内进行碎瘤,同时通过脐部摄像头进行检查。必须特别注意避免对袋子造成任何损坏,因为该技术中的视野有限。第二,描述一种直接视野技术,其中我们通过耻骨上套管针引出一个15毫米袋子的开口,通过脐部引出袋子的封闭端。我们在袋子的脐部末端开一个孔并通过它插入摄像头套管针。完成后,我们通过开口插入碎瘤器并将摄像头插入脐部端口。第三,解释一种单孔内置碎瘤术。袋子通过脐部引出,并放置一个皮肤牵开器。在牵开器外放置一只手套以隔离袋子。放置好后,张开两根手指用作套管针(一根用于碎瘤器,另一根用于30°摄像头)。使用该技术后,应更换窥镜以尽量减少污染风险。每种技术可能存在以下局限性:在间接视野技术中,由于视野有限,外科医生在碎瘤标本时必须特别注意避免撕裂袋子。在直接视野技术方法中,外科医生在将袋子从腹部取出之前需要确保袋子妥善封闭,以避免可能的播散风险。最后,在单孔技术中,外科医生必须有此类手术方法的既往经验,通过在碎瘤过程后更换窥镜将污染风险降至最低。

结论

在进行子宫切除术或多发性肌瘤切除术时,腹腔镜电动碎瘤术可能为我们的患者带来诸多益处。我们展示了3种使用内置袋容器进行腹腔镜电动碎瘤的不同且可行的技术。

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