使用恢复期血浆成功治愈 COVID-19 相关复发性腹泻和胃肠道出血。
Successful recovery of COVID-19-associated recurrent diarrhea and gastrointestinal hemorrhage using convalescent plasma.
机构信息
COVID-19 Research Center, Institute of Laboratory Medicine, Jinling Hospital, Nanjing University School of Medicine, the First School of Clinical Medicine, Southern Medical University, Nanjing, 210002, Jiangsu, China.
Department of Laboratory Medicine, Nanjing Red Cross Blood Center, Nanjing, 210003, Jiangsu, China.
出版信息
Mil Med Res. 2020 Sep 23;7(1):45. doi: 10.1186/s40779-020-00273-5.
BACKGROUND
Gastrointestinal symptoms are not rare among coronavirus disease 2019 (COVID-19) patients, but there have been no reports regarding convalescent plasma therapy for the recovery of gastrointestinal problems in COVID-19 patients.
CASE PRESENTATION
We present two cases of patients with COVID-19-associated recurrent diarrhea and positive fecal occult blood who successfully recovered after a one-time convalescent plasma administration.
CONCLUSION
When COVID-19 patients develop recurrent or refractory gastrointestinal symptoms and fail to respond to the available treatment, alternative therapy with convalescent plasma administration may be considered.
背景
胃肠道症状在新冠病毒病 2019（COVID-19）患者中并不罕见，但尚无关于恢复期血浆治疗 COVID-19 患者胃肠道问题的报告。
病例介绍
我们报告了两例 COVID-19 相关复发性腹泻和粪便潜血阳性的患者，在单次输注恢复期血浆后成功康复。
结论
当 COVID-19 患者出现反复或难治性胃肠道症状且对现有治疗无反应时，可考虑使用恢复期血浆输注作为替代治疗。
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