在未经治疗的霍奇金病中，PHA剂量依赖性地导致淋巴细胞刺激及E玫瑰花结形成细胞出现缺陷。
PHA dose dependent defect in lymphocyte stimulation and E-rosette-forming cells in untreated Hodgkin's disease.
作者信息
Land J M, Litwin J, Bigel P, Oberling F, Mayer S
出版信息
Acta Haematol Pol. 1977 May-Jun;8(2):131-4.
PMID:329629
Abstract
14 untreated patients with Hodgkin's disease were tested for lymphocte reactivity in vitro to optimal and suboptimal doses of PHA. A PHA dose-dependent defect in lymphocyte stimulation was demonstrated in patients when compared with a group of normal individuals. No correlation between the in vitro defect and decreased absolute number of E-rosette-forming cells (T-lymphocytes) in peripheral blood was found.
摘要
对14例未经治疗的霍奇金病患者进行了体外淋巴细胞对最佳和次最佳剂量PHA反应性的检测。与一组正常个体相比，患者表现出PHA剂量依赖性的淋巴细胞刺激缺陷。未发现体外缺陷与外周血中E花环形成细胞（T淋巴细胞）绝对数量减少之间存在相关性。
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PHA dose dependent defect in lymphocyte stimulation and E-rosette-forming cells in untreated Hodgkin's disease.在未经治疗的霍奇金病中，PHA剂量依赖性地导致淋巴细胞刺激及E玫瑰花结形成细胞出现缺陷。
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