Lymphocyte function in patients with Hodgkin's disease.

Lymphocyte functions in vitro were tested in patients with Hodgkin's disease. The PHA-induced lymphocyte stimulation and the responding capacity in the one-way mixed lymphocyte culture reaction was found to be severely depressed. In contrast, the PHA-induced production of a human mononuclear leukocyte chemotactic factor was not significantly impaired.