Reproductive Endocrinology and Infertility, Departement of Obstetrics and Gynaecology, Centre Hospitalier de l'Université de Montreal, Montréal, Québec, CANADA; Reproductive Endocrinology and Infertility, Departement of Obstetrics and Gynaecology, Clinique OVO Fertilité, Montréal, Québec, CANADA.
Reproductive Endocrinology and Infertility, Departement of Obstetrics and Gynaecology, Women's College Hospital, University of Toronto, Toronto, Ontario, CANADA; Reproductive Endocrinology and Infertility, Departement of Obstetrics and Gynaecology, Women's College Hospital, TRIO Fertility, Toronto, Ontario, CANADA.
Reprod Biomed Online. 2020 Nov;41(5):819-833. doi: 10.1016/j.rbmo.2020.08.007. Epub 2020 Aug 20.
Recurrent implantation failure (RIF) after IVF is a challenging topic for clinicians and can be a devastating reality for some patients with infertility. The purpose of this guideline from the Canadian Fertility and Andrology Society (CFAS) is to provide the most relevant evidence to date for the assessment and management of RIF. This guideline was developed using the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach. This guideline recognizes the presence of heterogeneity in the definition of RIF. Recommendations are offered here on the investigation of RIF and management options that may increase the chance of a live birth.
体外受精(IVF)后反复着床失败(RIF)是临床医生面临的一个具有挑战性的问题,对于一些不孕患者来说,这可能是一个毁灭性的现实。加拿大生育与男科协会(CFAS)的本指南旨在提供迄今为止与 RIF 的评估和管理最相关的证据。本指南使用 GRADE(推荐分级、评估、发展与评价)方法制定。本指南认识到 RIF 的定义存在异质性。本指南提供了 RIF 调查和管理选择的建议,这些选择可能增加活产的机会。