Department of Ophthalmology and Visual Sciences, University of Maryland School of Medicine, 419 West Redwood Street, Suite 479, Baltimore, MD, 21201, USA.
University of Maryland School of Medicine, 419 West Redwood Street, Suite 479, Baltimore, MD, 21201, USA.
Eye (Lond). 2021 Jan;35(1):265-276. doi: 10.1038/s41433-020-01184-4. Epub 2020 Sep 22.
Ultrasound biomicroscopy (UBM) is the only available option for noninvasive, high-resolution imaging of the intricate iridociliary complex, and for anterior segment imaging with corneal haze or opacity. While these unique features render UBM essential for specific types of trauma, congenital anomalies, and anterior segment tumors, UBM imaging has found clinical utility in a broad spectrum of diseases for structural assessments not limited to the anterior intraocular anatomy, but also for eyelid and orbit anatomy. This imaging tool has a very specific niche in the pediatric population where anterior segment disease can be accompanied by corneal opacity or clouding, and anomalies posterior to the iris may be present. Pediatric patients present additional diagnostic challenges. They are often unable to offer detailed histories or fully cooperate with examination, thus amplifying the need for high-resolution imaging. This purpose of this systematic review is to identify and synthesize the body of literature involving use of UBM to describe, evaluate, diagnose, or optimize treatment of pediatric ocular disease. The collated peer-reviewed research details the utility of this imaging modality, clarifies the structures and diseases most relevant for this tool, and describes quantitative and qualitative features of UBM imaging among pediatric subjects. This summary will include information about the specific applications available to enhance clinical care for pediatric eye disease.
超声生物显微镜（UBM）是唯一可用于无创、高分辨率成像复杂的虹膜睫状体复合体以及角膜混浊或不透明的眼前节成像的方法。虽然这些独特的功能使 UBM 成为特定类型的创伤、先天性异常和前节肿瘤的必要手段，但 UBM 成像在广泛的疾病中具有临床应用价值，不仅限于前眼内解剖结构，还包括眼睑和眼眶解剖结构。这种成像工具在儿科人群中具有非常特定的应用，在前节疾病可能伴有角膜混浊或混浊的情况下，虹膜后的异常可能存在。儿科患者还存在其他诊断挑战。他们通常无法提供详细的病史或完全配合检查，因此需要进行高分辨率成像。本系统评价的目的是确定并综合涉及使用 UBM 描述、评估、诊断或优化儿科眼部疾病治疗的文献。这些经过同行评审的研究详细介绍了这种成像方式的实用性，阐明了该工具最相关的结构和疾病，并描述了儿科患者 UBM 成像的定量和定性特征。本总结将包括有关特定应用的信息，以增强对儿科眼部疾病的临床护理。
