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Neutralization of P blood group antibodies by synthetic solid-phase antigens.

作者信息

Cowles J W, Blumberg N

出版信息

Transfusion. 1987 May-Jun;27(3):272-5. doi: 10.1046/j.1537-2995.1987.27387235638.x.

Abstract

P blood group system antibodies are encountered frequently in clinical transfusion practice. The authors describe an improved method for removing P antibodies from patient specimens without dilution. Solid-phase synthetic P antigens were used to neutralize serums containing P blood group system antibodies; 26 alloantibodies with specificity other than P were not inhibited. The synthetic P antigens are also used to characterize the heterogeneous immunochemical fine specificity of antibodies to P1 and P + P1 + Pk.

摘要

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