Chebli Selima, Zgueb Yosra, Ouali Uta, Taleb Sana, Nacef Fethi
Psychiatry Department A, Razi Hospital, Faculty of Medicine of Tunis, El Manar University of Tunis, Tunisia.
Case Rep Psychiatry. 2020 Sep 11;2020:8899615. doi: 10.1155/2020/8899615. eCollection 2020.
Neuropsychiatric manifestations in Sjögren's syndrome are common and can occur not only during its course, but also at the onset of the disease. Depression and anxiety were the most frequently described symptoms. However, the association with bipolar disorder seems to be rare and not well documented. This case report presents a patient with bipolar disorder as comorbidity with Sjögren's syndrome, suggesting that bipolar disorder could be associated with this autoimmune disease, which could lead to delaying diagnosis and treatment. A better analysis of the clinical background should be done by psychiatrists so to help early diagnosis and adapting prescription. Corticosteroids indicated in Sjögren's syndrome should be prescribed with caution in bipolar disorder.
干燥综合征的神经精神表现很常见，不仅可在病程中出现，也可在疾病发作时出现。抑郁和焦虑是最常被描述的症状。然而，与双相情感障碍的关联似乎很少见且记录不充分。本病例报告介绍了一名双相情感障碍合并干燥综合征的患者，提示双相情感障碍可能与这种自身免疫性疾病相关，这可能导致诊断和治疗延迟。精神科医生应更好地分析临床背景，以帮助早期诊断和调整处方。干燥综合征中使用的皮质类固醇在双相情感障碍中应谨慎使用。
