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以亚急性低氧血症为表现且呼吸功未增加的电子烟或雾化产品使用相关肺损伤

E-cigarette or Vaping Product Use-Associated Lung Injury Presenting as Sub-Acute Hypoxemia Without Increased Work of Breathing.

作者信息

Chawla Harmanpreet, Weiler Thomas

机构信息

Pediatrics/Critical Care, Presbyterian Hospital, Albuquerque, USA.

出版信息

Cureus. 2020 Aug 18;12(8):e9855. doi: 10.7759/cureus.9855.

DOI:10.7759/cureus.9855
PMID:32963897
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7500740/
Abstract

A 15-year-old male with a history of mild intermittent asthma presented with fatigue, coughing, vomiting and anorexia which was progressive in nature over the past month. The patient was found to have evolving chest x-ray infiltrates bilaterally, and hypoxemia without accessory muscle use. The patient was placed on non-invasive continuous positive airway pressure (CPAP) for hypoxemia. A CT scan showed bilateral infiltrates in a pattern consistent with E-cigarette or Vaping product use-Associated Lung Injury (EVALI). Upon further history taking, the patient admitted to electronic cigarette (e-cigarette) use with a new tetrahydrocannabinol (THC) cartridge prior to the onset of symptoms. The patient was started on methylprednisolone after which his oxygen requirement improved. This case highlights the need to continue to be diligent regarding the use of e-cigarettes in the pediatric population, and be aware of the constitutional symptoms that are associated with their use.

摘要

一名15岁男性,有轻度间歇性哮喘病史,出现疲劳、咳嗽、呕吐和厌食症状,在过去一个月里病情逐渐加重。患者胸部X光检查显示双侧有不断进展的浸润影,存在低氧血症但无辅助呼吸肌使用情况。因低氧血症,患者接受了无创持续气道正压通气(CPAP)治疗。CT扫描显示双侧浸润影,其模式与电子烟或雾化产品使用相关肺损伤(EVALI)一致。进一步询问病史时,患者承认在症状出现前使用了含新型四氢大麻酚(THC)烟弹的电子烟。患者开始使用甲泼尼龙治疗后,对氧气的需求有所改善。该病例凸显了在儿科人群中对电子烟使用持续保持警惕的必要性,并要意识到与使用电子烟相关的全身症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c608/7500740/cd5dc3353f2d/cureus-0012-00000009855-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c608/7500740/d8c8c5e850eb/cureus-0012-00000009855-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c608/7500740/b320ae369107/cureus-0012-00000009855-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c608/7500740/cd5dc3353f2d/cureus-0012-00000009855-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c608/7500740/d8c8c5e850eb/cureus-0012-00000009855-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c608/7500740/b320ae369107/cureus-0012-00000009855-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c608/7500740/cd5dc3353f2d/cureus-0012-00000009855-i03.jpg

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Demographics, Substance Use Behaviors, and Clinical Characteristics of Adolescents With e-Cigarette, or Vaping, Product Use-Associated Lung Injury (EVALI) in the United States in 2019.2019 年美国与电子烟或蒸气相关肺损伤(EVALI)的青少年的人口统计学、物质使用行为和临床特征。
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More on the Pathology of Vaping-Associated Lung Injury.更多关于电子烟相关肺损伤的病理学研究
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Update: Interim Guidance for Health Care Providers Evaluating and Caring for Patients with Suspected E-cigarette, or Vaping, Product Use Associated Lung Injury - United States, October 2019.更新:美国 2019 年 10 月,医疗保健提供者评估和护理疑似电子烟或蒸气产品使用相关肺损伤患者的临时指南。
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Notes from the Field: Use of Electronic Cigarettes and Any Tobacco Product Among Middle and High School Students - United States, 2011-2018.实地记录:2011 - 2018年美国初高中学生使用电子烟及其他烟草制品的情况
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