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与可卡因使用相关的双侧股骨头同时发生的缺血性坏死

Simultaneous Bilateral Avascular Necrosis of the Femoral Heads Associated With Cocaine Use.

作者信息

El-Yahchouchi Christine, Moussa Mohamad K, Khalaf Zaynab, Moussallem Charbel D

机构信息

Anesthesiology, American University of Beirut Medical Center, Beirut, LBN.

Orthopedic Surgery, Lebanese Hospital Geitaoui, University Medical Center, Beirut, LBN.

出版信息

Cureus. 2020 Aug 19;12(8):e9865. doi: 10.7759/cureus.9865.

DOI:10.7759/cureus.9865
PMID:32963906
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7500714/
Abstract

We present a case of a 38-year-old female patient, presenting with debilitating simultaneous bilateral avascular necrosis of the femoral head (AVNFH) 10 years after cocaine detoxification, making her wheelchair-bound for six months. This case is reported for the rarity of association of cocaine with AVNFH, and for the unique fact of the simultaneous bilateral condition occurring a long time after cocaine ingestion in the absence of other important risk factors. This report postulates cocaine as a possible cause of bilateral AVNFH, which can increase the index of suspicion of this pathology, allowing early diagnosis and better outcomes.

摘要

我们报告一例38岁女性患者,在可卡因戒毒10年后出现双侧股骨头缺血性坏死(AVNFH),导致其衰弱,需轮椅辅助六个月。报告此病例是因其可卡因与AVNFH关联罕见,且在无其他重要风险因素的情况下,双侧同时发病距可卡因摄入时间较长这一独特情况。本报告推测可卡因可能是双侧AVNFH的病因,这可提高对此病症的怀疑指数,从而实现早期诊断并改善预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/842c/7500714/665f0067411f/cureus-0012-00000009865-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/842c/7500714/496052a88fa1/cureus-0012-00000009865-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/842c/7500714/34fd9422f17c/cureus-0012-00000009865-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/842c/7500714/91fda82ccd30/cureus-0012-00000009865-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/842c/7500714/16080b818f40/cureus-0012-00000009865-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/842c/7500714/b90594748a7c/cureus-0012-00000009865-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/842c/7500714/5fb2a2bd6e6c/cureus-0012-00000009865-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/842c/7500714/665f0067411f/cureus-0012-00000009865-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/842c/7500714/496052a88fa1/cureus-0012-00000009865-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/842c/7500714/34fd9422f17c/cureus-0012-00000009865-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/842c/7500714/91fda82ccd30/cureus-0012-00000009865-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/842c/7500714/16080b818f40/cureus-0012-00000009865-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/842c/7500714/b90594748a7c/cureus-0012-00000009865-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/842c/7500714/5fb2a2bd6e6c/cureus-0012-00000009865-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/842c/7500714/665f0067411f/cureus-0012-00000009865-i07.jpg

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本文引用的文献

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Osteonecrosis of the femoral head: pathophysiology and current concepts of treatment.股骨头坏死:病理生理学与当前治疗理念
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2
Alcohol intake and the risk of osteonecrosis of the femoral head in Japanese populations: a dose-response meta-analysis of case-control studies.饮酒与日本人群股骨头坏死风险的关系:病例对照研究的剂量-反应荟萃分析。
Clin Rheumatol. 2017 Nov;36(11):2517-2524. doi: 10.1007/s10067-017-3740-4. Epub 2017 Jul 6.
3
Current concepts on osteonecrosis of the femoral head.
当前关于股骨头坏死的概念
World J Orthop. 2015 Sep 18;6(8):590-601. doi: 10.5312/wjo.v6.i8.590.
4
High triglyceride is a risk factor for silent osteonecrosis of the femoral head in systemic lupus erythematosus.高甘油三酯是系统性红斑狼疮患者股骨头无菌性坏死的一个危险因素。
Clin Rheumatol. 2015 Dec;34(12):2071-7. doi: 10.1007/s10067-015-3075-y. Epub 2015 Sep 18.
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Pathophysiology and risk factors for osteonecrosis.骨坏死的病理生理学与风险因素
Curr Rev Musculoskelet Med. 2015 Sep;8(3):201-9. doi: 10.1007/s12178-015-9277-8.
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High-Dose Corticosteroid Use and Risk of Hip Osteonecrosis: Meta-Analysis and Systematic Literature Review.大剂量使用皮质类固醇与髋部骨坏死风险:荟萃分析与系统文献综述
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Medical management of osteonecrosis of the hip: a review.髋关节骨坏死的医学管理:综述
Hip Int. 2011 Jul-Aug;21(4):385-92. doi: 10.5301/HIP.2011.8538.
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