Venishetty Nikit, Nguyen Ivy, Sohn Garrett, Bhalla Shubhang, Mounasamy Varatharaj, Sambandam Senthil
Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, 5001 El Paso Dr, El Paso, TX, USA.
University of Texas Southwestern, 5323 Harry Hines Blvd, Dallas, TX, USA.
J Orthop. 2023 Jul 26;43:64-68. doi: 10.1016/j.jor.2023.07.029. eCollection 2023 Sep.
Cocaine use has surged in the past decade, with 4.8 million Americans (1.7% of the population greater than 12) reporting use in 2021, leading to a healthcare burden of 1.3 billion dollars. Cocaine users experience prolonged hospital stays, higher costs, worse surgical outcomes, increased risk of medical conditions, and inflammation-related osteoarthritis. The study aims to identify factors influencing length of stay, costs, and perioperative complications in cocaine users undergoing total hip arthroplasty (THA) to reduce these risks.
This study utilized the NIS database, providing comprehensive information on patient demographics, length of stay, hospital costs, and complications. Statistical analyses were conducted using SPSS software, including propensity matching and significance testing, to compare outcomes between cocaine users (CU) and non-cocaine users (NCU) undergoing total hip arthroplasty.
After propensity matching, cocaine users had a significantly longer LOS (4.8 days) in comparison to non-cocaine users (2.6 days) (p < 0.001). Similarly, the CU group had a larger of care (87984.9) than the NCU group (69149.2) (p < 0.001). Cocaine users had significantly higher rates of blood loss anemia (OR: 3.24, 95% CI: 2.21, 4.73), blood loss anemia (OR: 1.59, 95% CI: 1.12, 2.24), blood transfusion (OR: 2.23, 95% CI: 1.04, 4.78), periprosthetic dislocation (OR: 6.57, 95% CI: 1.47, 29.32), and periprosthetic infection (OR: 4.59, 95% CI: 1.54, 13.68) than patients in the non-cocaine user's group.
Cocaine users had a significantly longer length of stay, higher costs of care, and an increased number of post-operative complications compared to non-cocaine users. These data contribute to understanding the potential ramifications of cocaine users undergoing THA.
在过去十年中，可卡因的使用量激增，2021年有480万美国人（占12岁以上人口的1.7%）报告使用过可卡因，导致了13亿美元的医疗负担。可卡因使用者住院时间延长、费用更高、手术结果更差、患疾病的风险增加，以及出现与炎症相关的骨关节炎。该研究旨在确定影响接受全髋关节置换术（THA）的可卡因使用者住院时间、费用和围手术期并发症的因素，以降低这些风险。
本研究使用了国家住院样本（NIS）数据库，该数据库提供了有关患者人口统计学、住院时间、医院费用和并发症的全面信息。使用SPSS软件进行统计分析，包括倾向匹配和显著性检验，以比较接受全髋关节置换术的可卡因使用者（CU）和非可卡因使用者（NCU）之间的结果。
经过倾向匹配后，与非可卡因使用者（2.6天）相比，可卡因使用者的住院时间明显更长（4.8天）（p < 0.001）。同样，CU组的护理费用（87984.9美元）高于NCU组（69149.2美元）（p < 0.001）。与非可卡因使用者组的患者相比，可卡因使用者发生失血贫血（比值比：3.24，95%置信区间：2.21，4.73）、失血（比值比：1.59，95%置信区间：1.12，2.24）、输血（比值比：2.23，95%置信区间：1.04，4.78）、假体周围脱位（比值比：6.57，95%置信区间：1.47，29.32）和假体周围感染（比值比：4.59，95%置信区间：1.54，13.68）的发生率显著更高。
与非可卡因使用者相比，可卡因使用者的住院时间明显更长，护理费用更高，术后并发症数量增加。这些数据有助于了解可卡因使用者接受THA的潜在后果。
