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癌胚抗原升高合并支气管阻塞,酷似肺癌——菜叶子惹的祸:病例报告。

Elevated carcinoembryonic antigen and bronchial obstruction caused by a rotten vegetable leaf mimic lung cancer: A case report.

机构信息

Department of Respiratory Medicine, North China University of Science and Technology Affiliated Hospital, Tangshan, China.

出版信息

J Clin Lab Anal. 2021 Jan;35(1):e23579. doi: 10.1002/jcla.23579. Epub 2020 Sep 22.

Abstract

BACKGROUND

Tracheobronchial foreign body aspiration is a potentially risky medical event, while the condition often requires early detection and rapid intervention to improve respiratory symptoms and prevent major morbidity. Notably, foreign bodies may not be identified and they are likely to be mistaken for neoplastic lesions. However, CEA, as one of tumor markers, presents to be available for assisting in lung cancer diagnosis, especially for non-small-cell lung cancer, while the specificity of CEA is not high.

METHODS

Here, we described a case of bronchial opening obstruction with elevated carcinoembryonic antigen (CEA) that was firstly misdiagnosed as lung cancer and proved as foreign body aspiration in the upper lobe bronchus of right lung by bronchoscopy.

RESULTS

Carcinoembryonic antigen level increased. CT scan demonstrated a cavitation accompanied by multiple small nodular shadows appeared in the right upper lobe field. Bronchoscopy suggested right upper lobe bronchus was blocked by a brown smooth organism with plenty of purulent materials, which was proved as a rotten vegetable leaf.

CONCLUSIONS

Elevated CEA and bronchial obstruction are not typical manifestations of lung cancer. Bronchoscopy is crucial for making a reliable diagnosis.

摘要

背景

气管支气管异物吸入是一种潜在危险的医疗事件,而这种情况通常需要早期发现和快速干预,以改善呼吸症状并预防严重的发病率。值得注意的是,异物可能无法被识别,并且可能被误诊为肿瘤病变。然而,CEA 作为肿瘤标志物之一,可用于辅助肺癌诊断,特别是非小细胞肺癌,而 CEA 的特异性不高。

方法

在这里,我们描述了一例因支气管开口阻塞导致癌胚抗原(CEA)升高的病例,该患者最初被误诊为肺癌,后来通过支气管镜检查证实为右肺上叶支气管异物吸入。

结果

癌胚抗原水平升高。CT 扫描显示右上肺野有空腔,伴有多个小结节阴影。支气管镜检查提示右上叶支气管被一个棕色光滑的物体阻塞,并有大量脓性物质,证实为腐烂的菜叶。

结论

CEA 升高和支气管阻塞不是肺癌的典型表现。支气管镜检查对于做出可靠的诊断至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e916/7843268/c6d55575e38f/JCLA-35-e23579-g001.jpg

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