Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, 0110, South Africa.
J Vet Emerg Crit Care (San Antonio). 2020 Nov;30(6):712-717. doi: 10.1111/vec.13008. Epub 2020 Sep 23.
To describe 2 cases of boomslang (Dispholidus typus) envenomation in dogs, with thromboelastographic evaluation performed both pre- and postadministration of monovalent antivenom, and to contrast the clinical application of thromboelastography (TEG) with that of conventional coagulation testing in 1 of these cases for monitoring coagulation status in dogs suffering from such envenomation.
Two dogs, a Weimeraner and a Dachshund, were referred, on separate occasions, for stabilization and treatment following observed boomslang envenomation. Initial physical examination revealed minor bleeding from the bite wound site in both dogs, along with mild swelling of the surrounding tissue. The Weimeraner also demonstrated bleeding from the gingival margin and had pale mucous membranes at time of presentation. Findings consistent with a diagnosis of disseminated intravascular coagulation (DIC) were noted on conventional coagulation testing. TEG tracings in both dogs revealed a hypocoagulable state preadministration of monovalent antivenom, followed by return to a normocoagulable state immediately postadministration, along with resolution of clinical bleeding. Both dogs were successfully discharged from the hospital, with no adverse reactions, either acute or delayed being noted.
Boomslang envenomation (hemotoxic snake venom) in dogs is rare, with currently only 3 cases in the literature. Herein, we document a further 2 cases and contrast changes on TEG with that noted on a routine hemostatic testing profile in 1 of these cases, to assess overall coagulation status both pre- and postadministration of antivenom.
描述 2 例狗类 boomslang(Dispholidus typus)中毒病例,对使用单价抗蛇毒血清前后进行血栓弹性描记术评估,并对比 1 例病例中血栓弹性描记术(TEG)与常规凝血检测的临床应用,以监测此类中毒犬的凝血状态。
2 只狗,一只魏玛犬和一只达克斯猎犬,分别因观察到 boomslang 中毒而被转诊进行稳定和治疗。初次体格检查发现两只狗的咬伤部位有轻微出血,周围组织有轻微肿胀。魏玛犬还表现出牙龈边缘出血,就诊时黏膜苍白。常规凝血检测发现弥散性血管内凝血(DIC)的特征性表现。两只狗的 TEG 描记图显示在使用单价抗蛇毒血清前存在低凝状态,随后在给药后立即恢复正常凝状态,同时临床出血得到解决。两只狗均成功出院,未出现急性或迟发性不良反应。
狗类的 boomslang 中毒(血液毒素蛇毒)罕见,目前文献中仅有 3 例。在此,我们进一步记录了另外 2 例,并对比其中 1 例的 TEG 变化与常规止血检测谱的变化,以评估在使用抗蛇毒血清前后的整体凝血状态。