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脊膜膨出

Meningocele

作者信息

Karsonovich Torin, Nethi Shashanka, Arya Kapil

机构信息

Baylor College of Medicine

Nassau University Medical Center

Abstract

Neural tube defects are the second most common type of congenital disability after congenital heart defects. Neural tube defects include meningoceles and myelomeningoceles, among others. Meningoceles are sacs of meninges containing cerebrospinal fluid that protrude into the subcutaneous tissue through a spinal defect, most of which are skin-covered. A complex meningocele is associated with other spinal anomalies, such as meningocele manque. Meningoceles are typically asymptomatic and are not associated with acute neurologic decline (see Types of Spina Bifida). Spinal dysraphism can be broadly categorized into open or closed depending on whether the lesion is covered by skin. Meningoceles and myelomeningoceles are examples of spina bifida aperta or open spina bifida. Some authors categorize meningoceles as open spina bifida, although some of these lesions are skin-covered. Spina bifida cystica is a subtype of spina bifida aperta and is characterized by a lesion within a meningeal lining, as seen in meningoceles and myleomeningoceles. An example of spina bifida aperta that does not fall under spina bifida cystica is myeloschisis, in which the spinal cord is exposed to the surface with no overlying spinal fluid sac. Spina bifida occulta, or closed spina bifida, can be seen in conditions such as split cord malformations, dorsal dermal sinus tracts, lipomyelomeningocele, and tight filum terminale. Myelomeningocele is the most common form of spina bifida, accounting for 90% of cases. Please see StatPearls' companion reference, "Myelomeningocele," for a more comprehensive discussion of that congenital disability.

摘要

神经管缺陷是仅次于先天性心脏病的第二常见先天性残疾类型。神经管缺陷包括脑脊膜膨出和脊髓脊膜膨出等。脑脊膜膨出是含有脑脊液的脑膜囊,通过脊柱缺损突入皮下组织,大多数有皮肤覆盖。复杂脑脊膜膨出与其他脊柱异常有关,如隐性脑脊膜膨出。脑脊膜膨出通常无症状,与急性神经功能衰退无关(见脊柱裂的类型)。脊柱裂根据病变是否有皮肤覆盖可大致分为开放性或闭合性。脑脊膜膨出和脊髓脊膜膨出是开放性脊柱裂或脊柱裂显性的例子。一些作者将脑脊膜膨出归类为开放性脊柱裂,尽管其中一些病变有皮肤覆盖。囊性脊柱裂是脊柱裂显性的一种亚型,其特征是脑膜内衬内有病变,如脑脊膜膨出和脊髓脊膜膨出所见。不属于囊性脊柱裂的脊柱裂显性的一个例子是脊髓裂,其中脊髓暴露于表面,没有覆盖的脑脊液囊。隐性脊柱裂或闭合性脊柱裂可见于诸如脊髓纵裂畸形、背侧皮窦道、脂肪瘤型脊髓脊膜膨出和终丝紧张等情况。脊髓脊膜膨出是脊柱裂最常见的形式,占病例的90%。有关该先天性残疾的更全面讨论,请参阅StatPearls的配套参考文献“脊髓脊膜膨出”。

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