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败血梭菌内源性眼内炎作为结直肠癌的初始表现:临床病例报告及文献综述

Clostridium Septicum Endogenous Endophthalmitis as the Initial Manifestation of Colorectal Carcinoma: Clinical Case Report and Literature Review.

作者信息

Sanchez-Vicente José L, Contreras-Díaz Miguel, López-Herrero Fernando, Martínez-Borrego Ana, Galván-Ledesma Antonio, Lozano-Bernal Oscar, García-Vazquez Mercedes, De Las Morenas-Iglesias Juan, Caro-Magdaleno Manuel

机构信息

Department of Ophthalmology , Virgen Del Rocío University Hospital, Seville, Spain.

Department of Ophthalmology, Virgen Macarena University Hospital, Seville, Spain.

出版信息

Ocul Immunol Inflamm. 2022 Feb 17;30(2):348-354. doi: 10.1080/09273948.2020.1799039. Epub 2020 Sep 23.

DOI:10.1080/09273948.2020.1799039
PMID:32966149
Abstract

PURPOSE

To describe the presentation and clinical course of a case of endogenous endophthalmitis caused by , an anaerobic and gram positive bacteria.

METHODS

Observational report of a clinical case presented in Spain.

CLINICAL CASE

A 61-year-old male patient was referred to our hospital with a diagnosis of endophthalmitis of his left eye since ten days prior to presentation, and a history of poor response to medical treatment. Evisceration was performed, and was isolated from a sample of the vitreous humor. Fourteen days after surgery, the patient returned with orbital cellulitis, and exenteration was performed. Forty-two days after initial presentation, colonoscopy revealed an adenocarcinoma of the proximal colon. Surgical resection of the tumor was performed, and clinical recovery was achieved.

CONCLUSIONS

iSystemic infection without a traumatic cause has been associated with malignancy, although an initial presentation of endophthalmitis has rarely been reported. In cases of clostridial endogenous endophthalmitis, investigation for colorectal carcinoma is indicated.

摘要

目的

描述由一种厌氧革兰氏阳性细菌引起的内源性眼内炎病例的临床表现和临床病程。

方法

对西班牙出现的一例临床病例的观察报告。

临床病例

一名61岁男性患者在就诊前10天被诊断为左眼眼内炎,并转诊至我院,且有对药物治疗反应不佳的病史。进行了眼球摘除术,并从玻璃体液样本中分离出[细菌名称未给出]。手术后14天,患者因眼眶蜂窝织炎再次就诊,并进行了眶内容剜除术。初次就诊42天后,结肠镜检查发现近端结肠腺癌。进行了肿瘤手术切除,患者临床康复。

结论

无创伤原因的全身性[细菌名称未给出]感染与恶性肿瘤有关,尽管内源性眼内炎的初次表现很少被报道。在梭菌性内源性眼内炎病例中,建议对结直肠癌进行调查。

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Fulminant endogenous panophthalmitis caused by Clostridium septicum infection.败血梭状芽孢杆菌感染引起的暴发性内源性全眼球炎。
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[Endogenous endophthalmitis as initial manifestation of invasive pneumococcal disease].
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Rev Esp Quimioter. 2021 Apr;34(2):154-155. doi: 10.37201/req/113.2020. Epub 2021 Jan 28.