Bai Xuechai, Li Yan, Li Xiaojing, Cao Siyu, Wang Liang
Department of Gynecology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
J Int Med Res. 2020 Sep;48(9):300060520959490. doi: 10.1177/0300060520959490.
Primary multiple obturator nerve schwannomas originate from Schwann cells and are extremely rare. Patients with schwannomas are asymptomatic and a retroperitoneal schwannoma is often misdiagnosed as an adnexal mass. In the present study, we describe a 58-year-old woman in whom a right adnexal mass accompanied by endometrial polyp was found incidentally through transvaginal ultrasound. The mass was diagnosed as multiple obturator nerve schwannomas after laparoscopy. Immunohistochemical assay confirmed the schwannomas to be positive for SOX10. To our knowledge, this is the first report to demonstrate a case of multiple schwannomas originating from the obturator nerve and treated by laparoscopic resection.
原发性多发性闭孔神经鞘瘤起源于施万细胞,极为罕见。患有神经鞘瘤的患者通常无症状,腹膜后神经鞘瘤常被误诊为附件肿物。在本研究中,我们描述了一名58岁女性,经阴道超声偶然发现其右侧附件肿物并伴有子宫内膜息肉。经腹腔镜检查,该肿物被诊断为多发性闭孔神经鞘瘤。免疫组织化学检测证实神经鞘瘤SOX10呈阳性。据我们所知,这是首例关于起源于闭孔神经的多发性神经鞘瘤并经腹腔镜切除治疗的病例报告。