Department of Rehabilitation Medicine, China-Japan Union Hospital of Jilin University, Changchun, China.
Department of General Surgery, The Second Hospital of Jilin University, Changchun Jilin, China.
J Int Med Res. 2022 Aug;50(8):3000605221119423. doi: 10.1177/03000605221119423.
Schwannoma is a type of tumor originating from Schwann cells of peripheral nerves. In this study, we report a rare case of two giant connected retroperitoneal schwannomas. The patient presented to our department with a 1-day history of abdominal pain and without other symptoms. There were no abnormalities in the patient's tumor markers. Abdominal plain computed tomography (CT) revealed two (combined) retroperitoneal masses appearing as soft tissue-density shadows with uneven internal density, cystic low-density shadows, and patchy calcification shadows. The larger mass measured approximately 12.0 cm × 12.3 cm in size. The tumors were completely excised by a reasonable surgical approach while the surrounding organs closely related to the tumor were preserved. Postoperative pathology confirmed that the tumors were benign schwannomas. In the 18-month follow-up, the patient had no recurrences and was asymptomatic. We summarize the diagnosis and treatment of two rare combined giant retroperitoneal schwannomas in a single patient. Laparotomy for the management of retroperitoneal giant schwannomas may be safe and effective.
神经鞘瘤是一种起源于周围神经施万细胞的肿瘤。本研究报告了一例罕见的双侧巨大连接性腹膜后神经鞘瘤。患者因腹痛 1 天就诊,无其他症状。肿瘤标志物无异常。腹部平扫 CT 显示两个(合并)腹膜后肿块,呈软组织密度影,内部密度不均匀,囊性低密度影,斑片状钙化影。较大的肿块大小约为 12.0cm×12.3cm。采用合理的手术入路完整切除肿瘤,同时保留与肿瘤密切相关的周围器官。术后病理证实肿瘤为良性神经鞘瘤。18 个月随访时,患者无复发,无症状。我们总结了一例罕见的双侧巨大连接性腹膜后神经鞘瘤的诊断和治疗。对于腹膜后巨大神经鞘瘤的治疗,剖腹手术可能是安全有效的。