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Dual effects of a gonadotropin-releasing hormone agonist on an adolescent girl with pelvic congestion syndrome and precocious puberty: a case report.

作者信息

Yu Jwo-Huey, Fang Hung-Hsiang, Liu Shih-Yao, Chang Wei-Chou, Liu Chiung-Chen, Lin Chien-Ming

机构信息

Department of Surgery, Taipei Veterans General Hospital, Taipei.

Department of Pediatrics, Tri-Service General Hospital, National Defense Medical Center, Taipei.

出版信息

J Int Med Res. 2020 Sep;48(9):300060520954694. doi: 10.1177/0300060520954694.

DOI:10.1177/0300060520954694
PMID:32967508
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7521058/
Abstract

Pelvic congestion syndrome (PCS) typically causes chronic non-cyclical abdominal pain with a considerable negative effect on the quality of life of women. However, pediatric cases with PCS are limited and non-invasive therapy for adolescent patients has not been reported. We report here a 13-year-old girl who presented with intermittent abdominal pain since the age of 2 years and her symptoms further deteriorated after breast development at 6 years and 9 months old. PCS and coexistent idiopathic central precocious puberty were finally diagnosed on the basis of tortuous ovarian and pelvic veins, and a pubertal response to a gonadotropin-releasing hormone (GnRH) test without hypothalamic-pituitary lesions. After treatment with the GnRH agonist, the pain score was greatly reduced and there was increased prediction of adult height. This case highlights the occurrence of PCS in adolescents and also indicates the role of non-invasive GnRH agonists in young patients with PCS before surgical intervention.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d94/7521058/9c84820943be/10.1177_0300060520954694-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d94/7521058/9c84820943be/10.1177_0300060520954694-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d94/7521058/9c84820943be/10.1177_0300060520954694-fig1.jpg

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Int J Occup Environ Health. 2014 Jan-Mar;20(1):33-45. doi: 10.1179/2049396713Y.0000000053.
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