From the Department of Surgery, Kumamoto Rosai Hospital, Yatsushiro, Kumamoto, Japan.
Exp Clin Transplant. 2021 Jan;19(1):88-91. doi: 10.6002/ect.2020.0126. Epub 2020 Sep 17.
Pancreatic neuroendocrine tumors are a rare type of tumor with malignant potential, characterized by slowgrowth, frequent hepatic metastatic lesions that usually stay contained within the liver. In patients with unresectable liver metastatic pancreatic neuroendocrine tumors, liver transplant is the only treatment available. Insulinomas are the most common pancreatic neuroendocrine tumors, and 5% to 10% of insulinomas are malignant. We herein report a case of a living-donor liver transplant with distal pancreatectomy for a patient with hepatic metastatic pancreatic insulinoma with a 13-year postoperative survival.
胰腺神经内分泌肿瘤是一种罕见的具有恶性潜能的肿瘤，其特点是生长缓慢，常有肝转移病灶，但通常局限于肝脏内。对于无法切除的肝转移胰腺神经内分泌肿瘤患者，肝移植是唯一的治疗方法。胰岛素瘤是最常见的胰腺神经内分泌肿瘤，其中 5%至 10%为恶性。本文报告了 1 例活体肝移植联合胰体尾切除术治疗肝转移胰腺胰岛素瘤患者的病例，患者术后生存 13 年。
