Anyfantakis Dimitrios, Symvoulakis Emmanouil K, Lionis Christos D
Primary Care, Primary Health Care Centre of Kissamos, Chania, GRC.
Social and Family Medicine, School of Medicine, University of Crete, Heraklion, GRC.
Cureus. 2020 Aug 21;12(8):e9910. doi: 10.7759/cureus.9910.
Telomere length (TL) represents an important marker of cellular aging. Its shortening affects human health and longevity by inducing senescence, apoptosis, and oncogenesis. Advanced ageing and negative behavioral and lifestyle factors decrease TL. The relationship between positive psycho-social factors and longer telomeres has given rise to a growing number of research efforts. Among these, religiosity poses a particular interest since it is associated with a wide range of favorable health outcomes. In this direction, recent literature reports, suggest a positive link between religiosity and TL. Underlying mechanisms for this association are not yet clarified. In this review, we would like to summarize the current knowledge on the link between religiosity and TL. Taking this opportunity, we recall findings from a cohort study in rural Crete, Greece that adds evidence on the discussion of potential psycho-social mediators which some may prevent shortening of TL.
端粒长度(TL)是细胞衰老的一个重要标志。其缩短通过诱导衰老、凋亡和肿瘤发生影响人类健康和寿命。高龄以及负面的行为和生活方式因素会缩短端粒长度。积极的心理社会因素与较长的端粒之间的关系引发了越来越多的研究。其中,宗教信仰尤其令人关注,因为它与广泛的良好健康结果相关。在这方面,最近的文献报道表明宗教信仰与端粒长度之间存在正相关。这种关联的潜在机制尚未阐明。在本综述中,我们将总结目前关于宗教信仰与端粒长度之间联系的知识。借此机会,我们回顾了希腊克里特岛农村一项队列研究的结果,该研究为关于某些可能防止端粒长度缩短的潜在心理社会调节因素的讨论增添了证据。