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财务激励措施在实现联合国艾滋病规划署 90-90-90 和 95-95-95 艾滋病毒护理连续体目标方面的效果:随机对照试验的系统评价和荟萃分析。

Effectiveness of Financial Incentives in Achieving UNAID Fast-Track 90-90-90 and 95-95-95 Target of HIV Care Continuum: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

机构信息

Department of Preventive and Social Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, 605006, India.

State Program and Technical Manager, Cap TB project, AP/TS Unit, Solidarity and Action against The HIV Infection in India (SAATHII), Hyderabad, India.

出版信息

AIDS Behav. 2021 Mar;25(3):814-825. doi: 10.1007/s10461-020-03038-2. Epub 2020 Sep 23.

Abstract

Financial incentives influence behavioural changes and the current review was done to assess the effectiveness of this intervention in improving HIV care continuum. We conducted systematic searches in MEDLINE, Cochrane library, ScienceDirect and Google Scholar from inception until July 2019. We carried out a meta-analysis with random-effects model quantifying inconsistency (I) for heterogeneity and reported pooled Risk Ratios (RR) with 95% confidence intervals (CIs). A total of 22 studies with 38,119 participants were included. All the six outcomes showed better results in financial incentive arm compared to standard care with statistical significance in three outcomes-HIV testing uptake (pooled RR: 2.42; 95%CI 1.06-5.54; I = 100%), antiretroviral therapy (ART) adherence (pooled RR: 1.30; 95%CI 1.13-1.50; I = 44%), and continuity in care (pooled RR: 1.24; 95%CI 1.09-1.41; I = 86%). To summarize, financial incentives can be helpful in improving the uptake of HIV testing, ART adherence and continuity of care while it was better for achieving viral load suppression among studies conducted in high-income countries.

摘要

经济激励措施可以影响行为的改变,而本综述旨在评估这种干预措施在改善艾滋病连续护理方面的效果。我们从创建之初到 2019 年 7 月,在 MEDLINE、Cochrane 图书馆、ScienceDirect 和 Google Scholar 中进行了系统检索。我们采用随机效应模型进行荟萃分析,量化异质性的不一致性(I),并报告了具有 95%置信区间(CI)的汇总风险比(RR)。共纳入 22 项研究,涉及 38119 名参与者。所有六项结局在经济激励组的结果均优于标准护理组,其中三项结局具有统计学意义:HIV 检测(汇总 RR:2.42;95%CI 1.06-5.54;I=100%)、抗逆转录病毒治疗(ART)依从性(汇总 RR:1.30;95%CI 1.13-1.50;I=44%)和连续护理(汇总 RR:1.24;95%CI 1.09-1.41;I=86%)。总的来说,经济激励措施有助于提高 HIV 检测的普及率、ART 的依从性和护理的连续性,而在高收入国家进行的研究中,经济激励措施更有助于实现病毒载量的抑制。

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