Department of Oncology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong Province, China.
Department of Oncology, The First Affiliated Hospital of Shandong First Medical University, Jinan, Shandong Province, China.
Asia Pac J Clin Oncol. 2020 Dec;16(6):320-325. doi: 10.1111/ajco.13419. Epub 2020 Sep 24.
Although surgical lobectomy with systematic mediastinal lymph node evaluation is considered as the "gold standard" for management of early stage non-small cell lung cancer (NSCLC), image-guided percutaneous thermal ablation has been increasingly used for medically inoperable patients. Radiofrequency ablation (RFA) is a research-based technique that has the most studies for medically inoperable early-stage NSCLC. Other thermal ablation techniques used to treat pulmonary tumors include microwave ablation (MWA), cryoablation and laser ablation. MWA has several advantages over RFA including reduced procedural time, reduced heat-sink effect, large ablation zones, decreased susceptibility to tissue impedance, and simultaneous use of multiple antennae. This review article highlights the most relevant updates of MWA for the treatment of early-stage NSCLC, including mechanism of action, clinical outcomes, potential complications, the existing technique problems and future directions.
虽然外科肺叶切除术伴系统性纵隔淋巴结评估被认为是早期非小细胞肺癌（NSCLC）治疗的“金标准”，但影像引导下经皮热消融已越来越多地用于不适宜手术的患者。射频消融（RFA）是一种基于研究的技术，针对不适宜手术的早期 NSCLC 有最多的研究。其他用于治疗肺肿瘤的热消融技术包括微波消融（MWA）、冷冻消融和激光消融。MWA 相对于 RFA 具有几个优势，包括减少手术时间、减少热沉效应、更大的消融区域、降低对组织阻抗的敏感性，以及同时使用多个天线。这篇综述文章重点介绍了 MWA 在治疗早期 NSCLC 方面的最新进展，包括作用机制、临床结果、潜在并发症、现有技术问题和未来方向。
