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[《药物性消化性溃疡临床诊疗指南(2020年修订版)》]

[Clinical Guidelines for Drug-induced Peptic Ulcer, 2020 Revised Edition].

作者信息

Joo Moon Kyung, Park Chan Hyuk, Kim Joon Sung, Park Jae Myung, Ahn Ji Yong, Lee Bong Eun, Lee Jeong Hoon, Yang Hyo-Joon, Cho Yu Kyung, Bang Chang Seok, Kim Beom Jin, Jung Hye-Kyung, Kim Byung-Wook, Lee Yong Chan

机构信息

Department of Internal Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.

Department of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea.

出版信息

Korean J Gastroenterol. 2020 Sep 25;76(3):108-133. doi: 10.4166/kjg.2020.76.3.108.

Abstract

The Korean guidelines for nonsteroidal anti-inflammatory drug (NSAID)-induced peptic ulcers were previously developed under co-work with the Korean College of and Upper Gastrointestinal Research and Korean Society of Gastroenterology at 2009. On the other hand, the previous guidelines were based mainly on a literature review and expert opinions. Therefore, the guidelines need to be revised. In this study, a guideline development committee for drug-induced peptic ulcers was organized under the Korean College of and Upper Gastrointestinal Research in 2017. Nine statements were developed, including four for NSAID, three for aspirin and other antiplatelet agents, and two for anticoagulants through processes based on evidence-based medicine, such as a literature search, meta-analysis, and the consensus was established using the modified Delphi method. The primary target of this guideline was adult patients taking long-term NSAIDs, aspirin, or other antiplatelet agent and anticoagulants. The revised guidelines reflect the consensus of expert opinions and are intended to assist relevant clinicians in the management and prevention of drug-induced peptic ulcers and associated conditions.

摘要

韩国非甾体抗炎药(NSAID)所致消化性溃疡指南先前于2009年由韩国胃肠病学与上消化道研究学会和韩国胃肠病学会合作制定。另一方面,先前的指南主要基于文献综述和专家意见。因此,该指南需要修订。在本研究中,2017年在韩国胃肠病学与上消化道研究学会的组织下成立了药物性消化性溃疡指南制定委员会。通过基于循证医学的过程,如文献检索、荟萃分析,制定了九条声明,其中四条针对NSAID,三条针对阿司匹林和其他抗血小板药物,两条针对抗凝剂,并使用改良的德尔菲法达成共识。本指南的主要目标是长期服用NSAID、阿司匹林或其他抗血小板药物及抗凝剂的成年患者。修订后的指南反映了专家意见的共识,旨在协助相关临床医生管理和预防药物性消化性溃疡及相关病症。

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