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经皮肾镜碎石术在儿科人群中的应用:单中心经验。

Percutaneous Nephrolithotomy in Paediatric Population: A Single Center Experience.

机构信息

Department of Urology, B and B Hospital, Gwarko, Lalitpur, Nepal.

出版信息

J Nepal Health Res Counc. 2020 Sep 7;18(2):205-209. doi: 10.33314/jnhrc.v18i2.2153.

Abstract

BACKGROUND

Management of paediatric stone disease is challenging as they are considered high risk group. Percutaneous nephrolithotomy is minimally invasive procedure with definite advantages in terms of higher stone clearance in single session and no long term effect in renal function.

METHODS

Retrospective study was done including all patients upto the age of 18 years who underwent Percutaneous nephrolithotomy from January 2010 to December 2018 in our center after taking approval from ethical committee. Data was collected regarding gender, operative side, operative time duration, hospital stay, post-operative decrease in hemoglobin, stone size, Guy's stone score and early post-operative complications with Clavien-Dindo grade.

RESULTS

Percutaneous nephrolithotomy was done in 48 renal units in 44 patients. 28 patients were boys and 16 were girls with mean age of 10.91 ± 5.22 years and mean stone size 17.16 ± 6.43 mm. 91.6% of cases had Guy's stone score of 1 and 2. Standard percutaneous nephrolithotomy was done in 21 renal units, mini percutaneous nephrolithotomy in 24 renal units and supermini percutaneous nephrolithotomy was done in three renal units with total stone free rate of 93.4%. Three patients required extracorporeal shockwave lithotripsy for significant residual stone. Average post-operative hemoglobin drop was 1.2 gm%. Overall complications rate was 18.1% with 4.5% of complications being grade 1 and 2 whereas 13.6% were Grade 3.

CONCLUSIONS

Percutaneous nephrolithotomy is safe and feasible in paediatric patients with large stone burden, complex anatomy or shock-wave lithotripsy failure with acceptable complication and stone free rate.

摘要

背景

儿童结石病的治疗具有挑战性,因为他们被认为是高风险群体。经皮肾镜碎石术是一种微创治疗方法,具有单次治疗结石清除率高、对肾功能无长期影响等优点。

方法

回顾性研究纳入了 2010 年 1 月至 2018 年 12 月在我中心接受经皮肾镜碎石术的所有 18 岁以下患者,研究获得了伦理委员会的批准。收集的数据包括性别、手术侧、手术时间、住院时间、术后血红蛋白下降、结石大小、Guys 结石评分和早期术后并发症(Clavien-Dindo 分级)。

结果

44 例患者共进行了 48 个肾脏单位的经皮肾镜碎石术。28 例为男性,16 例为女性,平均年龄为 10.91 ± 5.22 岁,平均结石大小为 17.16 ± 6.43mm。91.6%的病例 Guys 结石评分为 1 分和 2 分。标准经皮肾镜碎石术 21 个肾脏单位,微经皮肾镜碎石术 24 个肾脏单位,超细经皮肾镜碎石术 3 个肾脏单位,无石率为 93.4%。3 例患者因残留结石较大需要行体外冲击波碎石术。术后平均血红蛋白下降 1.2g%。总并发症发生率为 18.1%,其中 4.5%为 1 级和 2 级,13.6%为 3 级。

结论

经皮肾镜碎石术是一种安全可行的治疗方法,适用于有较大结石负荷、复杂解剖结构或体外冲击波碎石术失败的儿童患者,并发症发生率和无石率均可接受。

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