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脊髓间变性节细胞胶质瘤

Spinal anaplastic ganglioglioma.

作者信息

Khan Amad, Sadek Ahmed-Ramadan, Fabian Mark, Nader-Sepahi Ali

机构信息

Department of Neurosurgery, Wessex Neurological Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK.

Division of Clinical Neurosciences, School of Medicine, University of Southampton, Southampton, UK.

出版信息

Br J Neurosurg. 2023 Oct;37(5):1186-1189. doi: 10.1080/02688697.2020.1823936. Epub 2020 Sep 24.

Abstract

Anaplastic gangliogliomas of the spinal cord are extremely rare with only four cases reported in the literature. Here we present the case of a 22-year-old female who presented acutely with quadraparesis and urinary retention. Radiographic imaging demonstrated an intramedullary lesion within the cervical spine. She underwent a cervical laminectomy and resection of the lesion under neurophysiological monitoring. Post-operatively, she regained some function, but remained paraparetic. Histopathology demonstrated an anaplastic ganglioglioma (WHO Grade 3). She subsequently underwent radiotherapy. Following surgery, she remained stable and had MRC Grade 3 Power in all four limbs. Herein, we describe a previously undescribed case of cervical anaplastic ganglioglioma and review the existing literature.

摘要

脊髓间变性节细胞胶质瘤极为罕见,文献中仅报道过4例。本文报告了1例22岁急性出现四肢瘫和尿潴留的女性病例。影像学检查显示颈椎髓内有一病变。她在神经生理监测下接受了颈椎椎板切除术及病变切除术。术后,她恢复了一些功能,但仍有双下肢轻瘫。组织病理学显示为间变性节细胞胶质瘤(世界卫生组织3级)。随后她接受了放疗。手术后,她病情稳定,四肢肌力均为医学研究委员会3级。在此,我们描述了1例此前未描述过的颈椎间变性节细胞胶质瘤病例,并对现有文献进行了综述。

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