Khan Amad, Sadek Ahmed-Ramadan, Fabian Mark, Nader-Sepahi Ali
Department of Neurosurgery, Wessex Neurological Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Division of Clinical Neurosciences, School of Medicine, University of Southampton, Southampton, UK.
Br J Neurosurg. 2023 Oct;37(5):1186-1189. doi: 10.1080/02688697.2020.1823936. Epub 2020 Sep 24.
Anaplastic gangliogliomas of the spinal cord are extremely rare with only four cases reported in the literature. Here we present the case of a 22-year-old female who presented acutely with quadraparesis and urinary retention. Radiographic imaging demonstrated an intramedullary lesion within the cervical spine. She underwent a cervical laminectomy and resection of the lesion under neurophysiological monitoring. Post-operatively, she regained some function, but remained paraparetic. Histopathology demonstrated an anaplastic ganglioglioma (WHO Grade 3). She subsequently underwent radiotherapy. Following surgery, she remained stable and had MRC Grade 3 Power in all four limbs. Herein, we describe a previously undescribed case of cervical anaplastic ganglioglioma and review the existing literature.
脊髓间变性节细胞胶质瘤极为罕见，文献中仅报道过4例。本文报告了1例22岁急性出现四肢瘫和尿潴留的女性病例。影像学检查显示颈椎髓内有一病变。她在神经生理监测下接受了颈椎椎板切除术及病变切除术。术后，她恢复了一些功能，但仍有双下肢轻瘫。组织病理学显示为间变性节细胞胶质瘤（世界卫生组织3级）。随后她接受了放疗。手术后，她病情稳定，四肢肌力均为医学研究委员会3级。在此，我们描述了1例此前未描述过的颈椎间变性节细胞胶质瘤病例，并对现有文献进行了综述。
