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技术说明:血液辐照器的弗里克剂量测定法。

Technical Note: Fricke dosimetry for blood irradiators.

作者信息

Mantuano Andrea, Salata Camila, Mota Carla Lemos, Pickler Arissa, Pacífico Leonardo de Castro, Magalhães Luís Alexandre Gonçalves, Almeida Carlos Eduardo de

机构信息

Radiological Sciences Department, Rio de Janeiro State University (UERJ), Rio de Janeiro, Brazil.

Department of Medical and Research Facilities, National Nuclear Energy Authority (CNEN), Rio de Janeiro, Brazil.

出版信息

Med Phys. 2021 Jan;48(1):500-504. doi: 10.1002/mp.14487. Epub 2020 Dec 4.

Abstract

PURPOSE

The Fricke dosimeter has been shown to be a viable option as an absorbed dose standard. This work aims to provide the dose distribution in an irradiator container during blood irradiation using Fricke dosimetry.

METHODS

Measurements were performed using a Gammacell Elan 3000 blood irradiator at Hemocenter in Rio de Janeiro, Brazil. A specific phantom was constructed and patented by the authors to perform these measurements. Fricke solution was prepared according to international protocols, and polyethylene bags filled with Fricke solution (n = 19) were spatially distributed within the phantom. Control bags were also submitted to the same process, except the irradiation. The irradiation time was calculated to give 25.7 Gy to the central portion of the phantom, the same dose used for blood bags.

RESULTS

Encouraging results were obtained with an overall uncertainty of 2.1% (k = 1). The obtained results were compared with the doses calculated by the physicist from Hemocenter based on parameters provided by the manufacturer. The mean dose delivered to the Fricke bag in the center of the phantom (cavity 2) was 28.7 ± 0.5 Gy, which is 12% higher than the planned dose of 25.7 Gy.

CONCLUSIONS

The obtained results showed that the setup (Fricke and phantom) is able to perform dosimetry for blood irradiators. The delivered dose was higher than expected. This highlights the importance in controlling all the parameters during irradiation to ensure the correct dose for all irradiated bags.

摘要

目的

弗里克剂量计已被证明是一种可行的吸收剂量标准。本研究旨在利用弗里克剂量测定法提供血液辐照过程中辐照容器内的剂量分布情况。

方法

在巴西里约热内卢的血液中心,使用伽马细胞伊兰3000血液辐照器进行测量。作者构建了一个特定的体模并获得专利,用于进行这些测量。按照国际规程制备弗里克溶液,将装有弗里克溶液的聚乙烯袋(n = 19)在体模内进行空间分布。对照袋也经历相同过程,但不进行辐照。计算辐照时间,以使体模中心部位接受25.7 Gy的剂量,这与血袋所使用的剂量相同。

结果

获得了令人鼓舞的结果,总体不确定度为2.

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