用丙氨酸、TLD-100 和电离室评估血液辐照器的吸收剂量。

Absorbed dose evaluation of a blood irradiator with alanine, TLD-100 and ionization chamber.

机构信息

Post Graduate School in Medical Physics, University of Naples Federico II, 80131, Naples, Italy.

Post Graduate School in Medical Physics, University of Naples Federico II, 80131, Naples, Italy; National Institute of Nuclear Physics, 80126, Naples, Italy.

出版信息

Appl Radiat Isot. 2023 Oct;200:110981. doi: 10.1016/j.apradiso.2023.110981. Epub 2023 Aug 12.

DOI:10.1016/j.apradiso.2023.110981

PMID:37633189

Abstract

Irradiation of blood bags using X-ray irradiators and dosimetry services are required to ensure uniform dose levels in the range 25-50 Gy to prevent Transfusion Associated Graft versus Host Disease (TA-GvHD). An absorbed dose characterization of a Raycell MK2 X-Irradiator was performed using three different dosimetric systems. Results showed a dosimetric accuracy of the ionization chamber together with the Alanine dosimeter. TLDs measurements exhibited a small overestimation by 4% of the absorbed dose. The Dose Uniformity Ratio (DUR), between maximum and minimum dose levels in the canister, was in good agreement with the manufacturer specifications (≤1.5).

摘要

使用 X 射线辐照器和剂量测定服务对血袋进行辐照，以确保在 25-50 Gy 的范围内达到均匀的剂量水平，从而预防输血相关移植物抗宿主病（TA-GvHD）。使用三种不同的剂量测定系统对 Raycell MK2 X 辐照器进行了吸收剂量特性描述。结果表明，电离室与丙氨酸剂量计的剂量测定精度较高。TLDs 测量结果显示，吸收剂量的高估幅度较小，为 4%。罐内最大和最小剂量水平之间的剂量均匀性比（DUR）与制造商规格（≤1.5）非常吻合。