From the Departments of Radiology (E.A., M.K., S.E.J.C.).
Otolaryngology (I.P.), Guy's and St. Thomas' Hospital, London, United Kingdom.
AJNR Am J Neuroradiol. 2020 Nov;41(11):2126-2131. doi: 10.3174/ajnr.A6760. Epub 2020 Sep 24.
Otalgia may be secondary to serious pathology, such as upper aerodigestive tract malignancies, and CT or MR imaging of the skull base, face, and neck is often performed to detect clinically occult lesions. The diagnostic yield, management impact, and therapeutic impact of imaging in this clinical scenario, however, have yet to be elucidated.
CT and MR imaging in patients who presented with otalgia without clinically overt disease was retrospectively analyzed from a single center over a 9-year period. The cohort was subdivided into groups, depending on the presence of additional symptoms and a history of head and neck cancer. Relevant diagnostic outcome findings were categorized, and the diagnostic yield and impact of imaging on management and therapy were calculated for each group.
In our study cohort of 235 patients, the diagnostic yield of imaging for otalgia, with or without other symptoms, in patients who lacked a history of head and neck cancer was negligible for upper aerodigestive tract malignancy (1%), abnormalities related to otalgia (2%), and other moderate or major findings (2%). Although equivocal or unimportant findings occasionally resulted in additional investigations, the therapeutic impact was also very low (2%). The diagnostic yield for upper aerodigestive tract malignancy (34%) and therapeutic impact increased (34%) when there was a history of head and neck cancer.
The diagnostic yield and therapeutic impact of imaging for otalgia without clinically overt disease are very low, unless there is a history of head and neck cancer.
耳痛可能是上呼吸道消化道恶性肿瘤等严重疾病的继发症状,因此常对颅底、面部和颈部进行 CT 或 MR 成像,以检测临床隐匿性病变。然而,目前尚未阐明这种临床情况下影像学的诊断效果、管理影响和治疗影响。
对单中心 9 年间因耳痛而无明显临床疾病的患者进行 CT 和 MR 成像回顾性分析。根据是否存在其他症状和头颈部癌症史将队列分为不同组。对相关诊断结果进行分类,并计算每组的诊断效果和影像学对管理和治疗的影响。
在我们的 235 例研究患者中,无头颈部癌症史的患者中,影像学对耳痛的诊断效果(有无其他症状)对于上呼吸道消化道恶性肿瘤(1%)、与耳痛相关的异常(2%)和其他中度或重大发现(2%)的诊断效果可忽略不计。尽管偶有不确定或不重要的发现会导致进一步检查,但治疗影响也非常低(2%)。有头颈部癌症史时,上呼吸道消化道恶性肿瘤的诊断效果(34%)和治疗影响增加(34%)。
除非有头颈部癌症史,否则影像学对无明显临床疾病的耳痛的诊断效果和治疗影响非常低。