Osman Abdulfatah, Taipale Michael, Najjar Mazen, Osman Baraa
Department of Cardiovascular Medicine, 3452 Genesys Pkwy, Ascension Genesys Hospital, Grand Blanc, MI 48439, USA.
Division of Infectious Diseases, One Genesys Pkwy, Ascension Genesys Hospital, Grand Blanc, MI 48439, USA.
Access Microbiol. 2019 Jul 26;1(8):e000038. doi: 10.1099/acmi.0.000038. eCollection 2019.
prosthetic valve endocarditis is a rare infection caused by bacteria. This bacterium is found in the normal flora of the human mouth, gastrointestinal tract and female genital tract. While there have been isolated cases of bacteraemia and endocarditis, the infections are associated with comorbidities, immune deficiency, dental manipulation procedures and other medical history. This case of bioprosthetic valve endocarditis caused by is unusual, as the patient was immune-competent and treated with pre-procedural antibiotics.
We present a case of a 65-year-old male who underwent a dental extraction. He presented after 3 months of fever, chills and fatigue. On initial presentation, blood cultures were positive for alpha-haemolytic streptococcus bacteraemia. He was treated with IV penicillin and underwent aortic valve replacement with a bioprosthetic valve and excision of the mitral vegetation with repair of the mitral valve. Two years later, he had a tooth extraction after being treated properly with antibiotics. Three months later he presented with difficulty speaking, left leg weakness and increased drooling. All testing was normal. Three months later he presented with left side lower extremity weakness and expressive aphasia. He was diagnosed with bioprosthetic aortic valve endocarditis and was treated with IV penicillin and gentamicin for 6 weeks and then switched to oral penicillin. He remained stable.
can potentially be a cause of complicated endocarditis in patients with prosthetic heart valves undergoing dental procedures. Timely culture-guided antibiotic therapy is critical and may obviate the need for valve surgery.
人工瓣膜心内膜炎是一种由细菌引起的罕见感染。这种细菌存在于人类口腔、胃肠道和女性生殖道的正常菌群中。虽然有孤立的菌血症和心内膜炎病例,但这些感染与合并症、免疫缺陷、牙科操作程序及其他病史有关。这例由[细菌名称未给出]引起的生物人工瓣膜心内膜炎病例不同寻常,因为患者免疫功能正常且在术前接受了抗生素治疗。
我们报告一例65岁男性患者,他接受了拔牙手术。在出现发热、寒战和疲劳3个月后前来就诊。初次就诊时,血培养显示α溶血性链球菌菌血症阳性。他接受了静脉注射青霉素治疗,并接受了生物人工瓣膜主动脉瓣置换术以及二尖瓣赘生物切除和二尖瓣修复术。两年后,他在接受适当抗生素治疗后进行了拔牙。三个月后,他出现说话困难、左腿无力和流口水增多。所有检查均正常。三个月后,他出现左侧下肢无力和表达性失语。他被诊断为生物人工主动脉瓣心内膜炎,并接受了静脉注射青霉素和庆大霉素治疗6周,然后改为口服青霉素。他病情保持稳定。
对于接受牙科手术的人工心脏瓣膜患者,[细菌名称未给出]可能是导致复杂性心内膜炎的原因。及时的培养引导下的抗生素治疗至关重要,可能无需进行瓣膜手术。