加拿大侵袭性多重耐药（MDR）基因组种的鉴定与特征分析。
Identification and characterization of invasive multi-drug-resistant (MDR) genomospecies in Canada.
作者信息
Graham Christopher, Eshaghi Alireza, Sarabia Alicia, Zittermann Sandra, Stapleton Patrick, Kus Julianne V, Patel Samir N
机构信息
Trillium Health Partners, Mississauga ON, Canada.
Department of Medicine, University of Toronto, Toronto ON, Canada.
出版信息
Access Microbiol. 2020 Feb 26;2(5):acmi000111. doi: 10.1099/acmi.0.000111. eCollection 2020.
We identified and characterized a genome of the multi-drug-resistant genomospecies recovered from an invasive specimen from a hospitalized patient in Canada. The strain was resistant to penicillin, pipercillin-tazobactam, meropenem, clindaymycin and metronidazole. The strain harboured a plasmid containing the gene, which has been shown to be associated with metronidazole resistance. The study highlights the importance of being vigilant in suspecting antimicrobial drug resistance when a patient is not improving on therapy.
我们从加拿大一名住院患者的侵入性标本中鉴定并表征了一种多重耐药基因组种的基因组。该菌株对青霉素、哌拉西林-他唑巴坦、美罗培南、克林霉素和甲硝唑耐药。该菌株携带一个含有该基因的质粒，该基因已被证明与甲硝唑耐药性有关。该研究强调了在患者治疗无改善时警惕抗菌药物耐药性的重要性。
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