• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一种耐多药新型拟杆菌基因组种的特性分析

Characterization of a multidrug-resistant, novel Bacteroides genomospecies.

作者信息

Salipante Stephen J, Kalapila Aley, Pottinger Paul S, Hoogestraat Daniel R, Cummings Lisa, Duchin Jeffrey S, Sengupta Dhruba J, Pergam Steven A, Cookson Brad T, Butler-Wu Susan M

出版信息

Emerg Infect Dis. 2015 Jan;21(1):95-8. doi: 10.3201/eid2101.140662.

DOI:10.3201/eid2101.140662
PMID:25529016
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4285247/
Abstract

Metronidazole- and carbapenem-resistant Bacteroides fragilis are rare in the United States. We isolated a multidrug-resistant anaerobe from the bloodstream and intraabdominal abscesses of a patient who had traveled to India. Whole-genome sequencing identified the organism as a novel Bacteroides genomospecies. Physicians should be aware of the possibility for concomitant carbapenem- and metronidazole-resistant Bacteroides infections.

摘要

在美国,对甲硝唑和碳青霉烯耐药的脆弱拟杆菌很罕见。我们从一名去过印度的患者的血液和腹腔脓肿中分离出一种多重耐药厌氧菌。全基因组测序确定该菌株为一种新型拟杆菌基因组种。医生应意识到同时存在对碳青霉烯和甲硝唑耐药的拟杆菌感染的可能性。

相似文献

1
Characterization of a multidrug-resistant, novel Bacteroides genomospecies.一种耐多药新型拟杆菌基因组种的特性分析
Emerg Infect Dis. 2015 Jan;21(1):95-8. doi: 10.3201/eid2101.140662.
2
Characterisation of a multidrug-resistant Bacteroides fragilis isolate recovered from blood of a patient in Denmark using whole-genome sequencing.采用全基因组测序技术对丹麦血液感染患者的一株多药耐药脆弱拟杆菌分离株进行特征分析。
Int J Antimicrob Agents. 2015 Jul;46(1):117-20. doi: 10.1016/j.ijantimicag.2015.02.024. Epub 2015 Apr 17.
3
Fatal sepsis caused by multidrug-resistant Bacteroides fragilis, harboring a cfiA gene and an upstream insertion sequence element, in Japan.在日本,携带cfiA基因和上游插入序列元件的耐多药脆弱拟杆菌引起的致命性败血症。
Anaerobe. 2017 Apr;44:36-39. doi: 10.1016/j.anaerobe.2017.01.010. Epub 2017 Jan 17.
4
Metronidazole- and carbapenem-resistant bacteroides thetaiotaomicron isolated in Rochester, Minnesota, in 2014.2014年在明尼苏达州罗切斯特分离出的对甲硝唑和碳青霉烯耐药的嗜内脏拟杆菌。
Antimicrob Agents Chemother. 2015 Jul;59(7):4157-61. doi: 10.1128/AAC.00677-15. Epub 2015 May 4.
5
Molecular analysis of the carbapenem and metronidazole resistance mechanisms of Bacteroides strains reported in a Europe-wide antibiotic resistance survey.在一项全欧抗生素耐药性调查中报告的拟杆菌属菌株对碳青霉烯类和甲硝唑耐药机制的分子分析。
Int J Antimicrob Agents. 2013 Feb;41(2):122-5. doi: 10.1016/j.ijantimicag.2012.10.001. Epub 2012 Nov 14.
6
First report of metronidazole resistant, nimD-positive, Bacteroides stercoris isolated from an abdominal abscess in a 70-year-old woman.从一名70岁女性腹部脓肿中分离出甲硝唑耐药、nimD阳性的硬结拟杆菌的首例报告。
Anaerobe. 2017 Feb;43:91-93. doi: 10.1016/j.anaerobe.2016.12.010. Epub 2016 Dec 21.
7
Molecular characterisation of multidrug-resistant Bacteroides isolates from Hungarian clinical samples.从匈牙利临床样本中分离出的多重耐药拟杆菌的分子特征。
J Glob Antimicrob Resist. 2018 Jun;13:65-69. doi: 10.1016/j.jgar.2017.10.020. Epub 2017 Oct 31.
8
Susceptibility profiles and resistance genes for carbapenems (cfiA) and metronidazole (nim) among Bacteroides species in a Turkish University Hospital.土耳其某大学医院拟杆菌属中碳青霉烯类(cfiA)和甲硝唑(nim)的药敏谱和耐药基因。
Anaerobe. 2012 Feb;18(1):169-71. doi: 10.1016/j.anaerobe.2011.10.004. Epub 2011 Oct 31.
9
Multidrug-resistant bacteroides fragilis--Seattle, Washington, 2013.艰难梭菌耐药菌株——华盛顿州西雅图,2013 年。
MMWR Morb Mortal Wkly Rep. 2013 Aug 30;62(34):694-6.
10
Two cases of infections due to multidrug-resistant Bacteroides fragilis group strains.两例由耐多药脆弱拟杆菌群菌株引起的感染病例。
J Clin Microbiol. 2006 Sep;44(9):3465-7. doi: 10.1128/JCM.00316-06.

引用本文的文献

1
Genomic Background and Phylogeny of A-Positive Strains Resistant to Meropenem-EDTA.对美罗培南-EDTA耐药的A阳性菌株的基因组背景和系统发育
Antibiotics (Basel). 2021 Mar 16;10(3):304. doi: 10.3390/antibiotics10030304.
2
Improved Metagenomic Taxonomic Profiling Using a Curated Core Gene-Based Bacterial Database Reveals Unrecognized Species in the Genus .使用基于精选核心基因的细菌数据库改进宏基因组分类分析揭示了该属中未被识别的物种。
Pathogens. 2020 Mar 10;9(3):204. doi: 10.3390/pathogens9030204.
3
Application of the Whole Genome-Based Bacterial Identification System, TrueBac ID, Using Clinical Isolates That Were Not Identified With Three Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) Systems.

本文引用的文献

1
The SEED and the Rapid Annotation of microbial genomes using Subsystems Technology (RAST).SEED 与利用子系统技术进行快速微生物基因组注释(RAST)。
Nucleic Acids Res. 2014 Jan;42(Database issue):D206-14. doi: 10.1093/nar/gkt1226. Epub 2013 Nov 29.
2
Multidrug-resistant bacteroides fragilis--Seattle, Washington, 2013.艰难梭菌耐药菌株——华盛顿州西雅图,2013 年。
MMWR Morb Mortal Wkly Rep. 2013 Aug 30;62(34):694-6.
3
Two multidrug-resistant clinical isolates of Bacteroides fragilis carry a novel metronidazole resistance nim gene (nimJ).
应用全基因组细菌鉴定系统 TrueBac ID 鉴定三种基质辅助激光解吸电离飞行时间质谱(MALDI-TOF MS)系统无法鉴定的临床分离株。
Ann Lab Med. 2019 Nov;39(6):530-536. doi: 10.3343/alm.2019.39.6.530.
4
CRISPR-Cas Systems in , an Important Pathobiont in the Human Gut Microbiome.人类肠道微生物群中的重要病理共生菌——[具体名称未给出]中的CRISPR-Cas系统 。 (你提供的原文似乎不完整,“in”后面缺少具体内容)
Front Microbiol. 2017 Nov 23;8:2234. doi: 10.3389/fmicb.2017.02234. eCollection 2017.
5
Identification and Antimicrobial Susceptibility Testing of Anaerobic Bacteria: Rubik's Cube of Clinical Microbiology?厌氧菌的鉴定及药敏试验:临床微生物学的魔方?
Antibiotics (Basel). 2017 Nov 7;6(4):25. doi: 10.3390/antibiotics6040025.
6
A Novel Selective Medium for Isolation of Bacteroides fragilis from Clinical Specimens.一种用于从临床标本中分离脆弱拟杆菌的新型选择性培养基。
J Clin Microbiol. 2017 Feb;55(2):384-390. doi: 10.1128/JCM.01988-16. Epub 2016 Nov 16.
7
A Year of Infection in the Intensive Care Unit: Prospective Whole Genome Sequencing of Bacterial Clinical Isolates Reveals Cryptic Transmissions and Novel Microbiota.重症监护病房的感染一年:细菌临床分离株的前瞻性全基因组测序揭示隐匿传播和新型微生物群
PLoS Genet. 2015 Jul 31;11(7):e1005413. doi: 10.1371/journal.pgen.1005413. eCollection 2015 Jul.
8
Metronidazole- and carbapenem-resistant bacteroides thetaiotaomicron isolated in Rochester, Minnesota, in 2014.2014年在明尼苏达州罗切斯特分离出的对甲硝唑和碳青霉烯耐药的嗜内脏拟杆菌。
Antimicrob Agents Chemother. 2015 Jul;59(7):4157-61. doi: 10.1128/AAC.00677-15. Epub 2015 May 4.
脆弱拟杆菌的两株多药耐药临床分离株携带一种新型甲硝唑耐药 nim 基因(nimJ)。
Antimicrob Agents Chemother. 2013 Aug;57(8):3767-74. doi: 10.1128/AAC.00386-13. Epub 2013 May 28.
4
Identification of acquired antimicrobial resistance genes.获得性抗菌耐药基因的鉴定。
J Antimicrob Chemother. 2012 Nov;67(11):2640-4. doi: 10.1093/jac/dks261. Epub 2012 Jul 10.
5
BLAST Ring Image Generator (BRIG): simple prokaryote genome comparisons.BLAST 环图像生成器(BRIG):简单的原核生物基因组比较。
BMC Genomics. 2011 Aug 8;12:402. doi: 10.1186/1471-2164-12-402.
6
Update on resistance of Bacteroides fragilis group and related species with special attention to carbapenems 2006-2009.2006-2009 年脆弱拟杆菌群及相关物种对碳青霉烯类药物耐药性的研究进展
Anaerobe. 2011 Aug;17(4):147-51. doi: 10.1016/j.anaerobe.2011.05.014. Epub 2011 Jun 2.
7
Multi-drug resistant Bacteroides fragilis recovered from blood and severe leg wounds caused by an improvised explosive device (IED) in Afghanistan.从血液和阿富汗简易爆炸装置(IED)造成的严重腿部创伤中分离出的多药耐药脆弱拟杆菌。
Anaerobe. 2011 Aug;17(4):152-5. doi: 10.1016/j.anaerobe.2011.02.007. Epub 2011 Mar 3.
8
Antimicrobial susceptibility of Bacteroides fragilis group isolates in Europe: 20 years of experience.欧洲脆弱拟杆菌群分离株的抗菌药敏性:20 年的经验。
Clin Microbiol Infect. 2011 Mar;17(3):371-9. doi: 10.1111/j.1469-0691.2010.03256.x.
9
Shifting the genomic gold standard for the prokaryotic species definition.动摇原核生物种定义的基因组黄金标准。
Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):19126-31. doi: 10.1073/pnas.0906412106. Epub 2009 Oct 23.
10
Metronidazole resistance in Prevotella spp. and description of a new nim gene in Prevotella baroniae.普雷沃氏菌属中的甲硝唑耐药性及巴氏普雷沃氏菌中新型 nim 基因的描述。
Antimicrob Agents Chemother. 2010 Jan;54(1):60-4. doi: 10.1128/AAC.01003-09. Epub 2009 Oct 5.