Department of Moalajat, National Institute of Unani Medicine, Bangalore, 560091, India.
Drug Metab Pers Ther. 2020 Jul 21;35(3):dmpt-2020-0123. doi: 10.1515/dmpt-2020-0123.
Hypothyroidism is the most common thyroid disorder, affects women more frequently, and incidence increases with age. The prevalence of hypothyroidism in developed countries is around 4-5%, whereas, in India, it is about 11%. The common symptoms of hypothyroidism in adults are weight gain, fatigue, lethargy, cold intolerance, constipation, change in voice, and dry skin. It can affect all systems of the body. Diagnosis is mainly based on clinical history and laboratory investigations. Untreated hypothyroidism increases morbidity and mortality. In conventional medicine, the treatment of choice is Levothyroxine, whereas in Unani System of Medicine, pharmacotherapy consists of single and compound drugs. Single drugs are selected as per the constitution (Mizaj) of drugs as opposed to the abnormal constitution (Su-e-Mizaj) of disease and its pathology. Some drugs increase the basal metabolic rate whereas some evacuate the morbid material from the body by the action of purgation. The drugs are used either in a single form or as a prescription of more than one drug in the form of decoction (Joshandah), infusion (Kheshandah), or powder (Safoof). This review aims at providing comprehensive information regarding various drugs used in Unani system of medicine that is used in the management of thyroid dysfunction.
甲状腺功能减退症是最常见的甲状腺疾病，女性更易患病，且发病率随年龄增长而增加。在发达国家，甲状腺功能减退症的患病率约为 4-5%，而在印度，约为 11%。成人甲状腺功能减退症的常见症状包括体重增加、疲劳、乏力、怕冷、便秘、声音改变和皮肤干燥。它可影响身体的所有系统。诊断主要基于临床病史和实验室检查。未经治疗的甲状腺功能减退症会增加发病率和死亡率。在常规医学中，治疗选择是左旋甲状腺素，而在尤纳尼医学系统中，药物治疗包括单药和复方药物。单药是根据药物的体质（Mizaj）选择的，而不是根据疾病及其病理的异常体质（Su-e-Mizaj）选择的。一些药物会提高基础代谢率，而另一些药物则通过泻下作用将病态物质从体内排出。这些药物要么单独使用，要么以汤剂（Joshandah）、浸剂（Kheshandah）或粉末（Safoof）的形式使用一种以上药物的处方形式使用。本综述旨在提供有关尤纳尼医学系统中用于治疗甲状腺功能障碍的各种药物的全面信息。
