Department of Dermatology and Venereology, Faculty of Medicine, Trakya University, Edirne, Turkey.
Acta Dermatovenerol Alp Pannonica Adriat. 2020 Sep;29(3):149-151.
Lichen sclerosus, a rare, chronic, inflammatory, mucocutaneous disorder of the genital and extragenital skin, is usually asymptomatic and affects both sexes. The exact cause of lichen sclerosus is unknown. Extragenital lichen sclerosus may be localized or disseminated. Linear extragenital lichen sclerosus following the lines of Blaschko is an exceptionally rare form. A 66-year-old female patient presented with a sclerotic plaque extending from the dorsum of the right hand toward the elbow. The lesion first appeared on the right hand but spread toward the elbow within 1 year. The histological findings were consistent with a diagnosis of lichen sclerosus. We therefore diagnosed extragenital linear lichen sclerosus and achieved a good response with methotrexate.
硬化性苔藓，一种罕见的、慢性的、炎症性的、黏膜和皮肤的疾病，通常是无症状的，影响两性。硬化性苔藓的确切原因尚不清楚。外阴硬化性苔藓可局限或播散。沿着 Blaschko 线分布的外阴硬化性苔藓是一种极为罕见的形式。一名 66 岁女性患者出现了一个从右手背部向肘部延伸的硬化斑块。该病变最初出现在右手，但在 1 年内向肘部扩散。组织学检查结果符合硬化性苔藓的诊断。因此，我们诊断为外阴线性硬化性苔藓，并使用甲氨蝶呤获得了良好的疗效。
