National Institutes of Health, Bethesda, Maryland (A.K.P., P.C., H.C.L., H.M., K.S.).
Icahn School of Medicine at Mount Sinai, New York, New York (J.A.).
Ann Intern Med. 2021 Jan;174(1):93-95. doi: 10.7326/M20-6448. Epub 2020 Sep 25.
In the United States, the efficacy and safety of convalescent plasma for treating coronavirus disease 2019 (COVID-19) is currently being tested in randomized placebo-controlled clinical trials. Treatment of individual patients with COVID-19 with convalescent plasma outside such trials is also now permitted through U.S. Food and Drug Administration Emergency Use Authorization. Here, members of the National Institutes of Health COVID-19 Treatment Guidelines Panel provide their views regarding use of convalescent plasma for treating COVID-19.
在美国,恢复期血浆治疗 2019 年冠状病毒病(COVID-19)的疗效和安全性目前正在随机安慰剂对照临床试验中进行测试。在美国食品和药物管理局(FDA)紧急使用授权下,现在也允许在这些试验之外,对 COVID-19 患者个体使用恢复期血浆进行治疗。在此,美国国立卫生研究院(NIH)COVID-19 治疗指南专家组的成员提供了他们对使用恢复期血浆治疗 COVID-19 的看法。